Protein Info for Dsui_3346 in Dechlorosoma suillum PS

Annotation: putative signal transduction protein containing EAL and modified HD-GYP domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 420 PF00563: EAL" amino acids 16 to 200 (185 residues), 49.1 bits, see alignment E=5e-17 PF08668: HDOD" amino acids 224 to 332 (109 residues), 47.1 bits, see alignment E=2.1e-16

Best Hits

KEGG orthology group: K07181, putative signal transduction protein containing EAL and modified HD-GYP domains (inferred from 54% identity to dar:Daro_3300)

Predicted SEED Role

"Predicted signal transduction protein" in subsystem Flagellar motility

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QJZ7 at UniProt or InterPro

Protein Sequence (420 amino acids)

>Dsui_3346 putative signal transduction protein containing EAL and modified HD-GYP domains (Dechlorosoma suillum PS)
MAPDTTHTTPIYLGRQPILDARQSLYGYELLFRSGPAPNRAIVANHMVATATVITHAFTE
LGLADALGEQKAFINVDGDFLLSEAVELLPKDKVVLEILETVEVTPELLKRCRELKAKGF
TLALDDIVAVTPAMEPLLDLMDIAKVCISAVSEEALPGLVQALARRPLELLAEQVESREQ
MEHCRNLGFHLFQGYYFAHPTILSGRKLGQSRLSLLKLLSQVLDDSDTPQLEQTFKHEPG
LSINLLRMANSAAVGARTRITSLRHAITLLGRRQLQRWLQLLLYTDPAGNTGFPPLLQLA
ATRARLLELLAESHMAADRDFADRAFMTGILSLTPALFATPIDEILSQISTLATDVKQAL
LRHQGSLGLLLRLIEALESEDLSQVPALVAQLPGLSPERVNLAQAQALAWTRAIGQEQQN