Protein Info for Dsui_3345 in Dechlorosoma suillum PS

Annotation: putative signal transduction protein containing EAL and modified HD-GYP domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 transmembrane" amino acids 321 to 339 (19 residues), see Phobius details PF00563: EAL" amino acids 86 to 197 (112 residues), 39.9 bits, see alignment E=3.3e-14 PF08668: HDOD" amino acids 220 to 275 (56 residues), 31.9 bits, see alignment 9.4e-12

Best Hits

KEGG orthology group: K07181, putative signal transduction protein containing EAL and modified HD-GYP domains (inferred from 50% identity to dar:Daro_3300)

Predicted SEED Role

"Predicted signal transduction protein" in subsystem Flagellar motility

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QJZ6 at UniProt or InterPro

Protein Sequence (414 amino acids)

>Dsui_3345 putative signal transduction protein containing EAL and modified HD-GYP domains (Dechlorosoma suillum PS)
MMLPLDADIFLARQPILDREQKLVAYELLFRSSGVDRAAVADGRLATARVVANAFGEMSL
GDVLGPYKAYINATPDFVLGPEVEILPGASVVLELPADTPADEALLARCRELKQQGFTFA
LGGVAEFAEINLPLLPEAEILKVDHQLLDNHQLFLLACKLRPLQKKLLAEKIENQSQMEH
CFDLGFEYFQGYYFARPTLISGKKLTHSAMTVMRLLDLILKDADTAALERSFKGEPGLTL
NLLRLTNSCASGLAVRIASVRHAITILGRNQLQRWLQLLLYADPEGGEVGPLLQLAATRG
RFLELVTQKFLPRQKDLPDRAFMVGILSLLPAVIGQPIADIITPLPLPPDVKQALIEYKG
DLGRLLALAEQLEKADGDATFNGLIAEMPGLRGALLTECLAQAMAWANMLARDS