Protein Info for Dsui_3255 in Dechlorosoma suillum PS

Annotation: integral membrane protein MviN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 514 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 27 to 47 (21 residues), see Phobius details amino acids 90 to 113 (24 residues), see Phobius details amino acids 134 to 153 (20 residues), see Phobius details amino acids 161 to 182 (22 residues), see Phobius details amino acids 188 to 208 (21 residues), see Phobius details amino acids 229 to 254 (26 residues), see Phobius details amino acids 274 to 292 (19 residues), see Phobius details amino acids 313 to 334 (22 residues), see Phobius details amino acids 354 to 375 (22 residues), see Phobius details amino acids 386 to 405 (20 residues), see Phobius details amino acids 411 to 431 (21 residues), see Phobius details amino acids 443 to 464 (22 residues), see Phobius details amino acids 481 to 501 (21 residues), see Phobius details TIGR01695: murein biosynthesis integral membrane protein MurJ" amino acids 3 to 504 (502 residues), 511.8 bits, see alignment E=1.1e-157 PF03023: MurJ" amino acids 28 to 479 (452 residues), 482 bits, see alignment E=8e-149

Best Hits

Swiss-Prot: 62% identical to MURJ_SALTY: Probable lipid II flippase MurJ (murJ) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03980, virulence factor (inferred from 75% identity to dar:Daro_0708)

MetaCyc: 63% identical to lipid II flippase MurJ (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-286

Predicted SEED Role

"Proposed peptidoglycan lipid II flippase MurJ" in subsystem ZZ gjo need homes

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QJB8 at UniProt or InterPro

Protein Sequence (514 amino acids)

>Dsui_3255 integral membrane protein MviN (Dechlorosoma suillum PS)
MNLLRALVTVSGMTLLSRLLGFVRDFVIARAFGAGLATDAFFVAFKLPNLLRRLFAEGAF
SQAFVPILGEYKNRRGEEEARHLVDRVATLLFLILTLVTALGVAGAPILVYISAPGFAAE
AEKFELTVTLTRITFPYILFMSLVALSGGILNTWSRFALPAFTPVLLNVSFIALALFATP
WFDQPALVLGWAVFVGGVLQLGLQLPALRRIGMLPRFRFDWKDEGVRRILRLMAPAVLGV
SVSQVSLLINTVFASFLQSGSVSWLYYADRLMEFPSGLLGAALGTILLPSLAKYHADGKG
EDYARLLDWGLRLCLLLTLPAALALAILGVPLIATLFHHGAFTGADVFHTRDALAAYAVG
LTGLILVKVLAPGFYARQNIRTPVKIALASLCATQAMNLLFVVLLDLDHAGLALSIGLAA
CLNAFLLYRGLRRHDIYRPQAGWLPFLLKLLAALAVLGAALWLGMGREADWLLYSTLQRL
LHLGALVAGGIFAYFATLYALGFRMRDFKRRAAE