Protein Info for Dsui_3128 in Dechlorosoma suillum PS

Annotation: ribonuclease R

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 828 TIGR02063: ribonuclease R" amino acids 28 to 726 (699 residues), 881 bits, see alignment E=6.3e-269 TIGR00358: VacB and RNase II family 3'-5' exoribonucleases" amino acids 75 to 724 (650 residues), 749.9 bits, see alignment E=2.2e-229 PF08206: OB_RNB" amino acids 95 to 152 (58 residues), 77.3 bits, see alignment 1.5e-25 PF17876: CSD2" amino acids 172 to 252 (81 residues), 80 bits, see alignment E=2.8e-26 PF00773: RNB" amino acids 274 to 601 (328 residues), 371.9 bits, see alignment E=7.6e-115 PF00575: S1" amino acids 643 to 723 (81 residues), 41.9 bits, see alignment E=2.6e-14

Best Hits

KEGG orthology group: K12573, ribonuclease R [EC: 3.1.-.-] (inferred from 75% identity to dar:Daro_2972)

Predicted SEED Role

"3'-to-5' exoribonuclease RNase R" in subsystem RNA processing and degradation, bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QI59 at UniProt or InterPro

Protein Sequence (828 amino acids)

>Dsui_3128 ribonuclease R (Dechlorosoma suillum PS)
MSTRKLSKTRKNDPFFERECQKYEIPLPSREYTMQLLQDQGRPVSFDQLVALLDISRDEE
DLFQRRLNAMERDGQLLRNRKNSYILPEKADLIPGKVEGHPDGFGFVKPDDGSDDLFLEP
KQMDKVLHGDRVLVRCIGLDRRGRREATIVEVLERANTRLVGRLMEEHGIQFVVAENKRI
SQDILIPPTAMTDKRAKLKARPGNVVMVEILEQPSRYSQPIGRIVEILGNYADPGMEIEI
ALRKHDLPFEFSKEAQAENKAVPDKVKKSDFKGREDLRELPLVTIDGETARDFDDAVFCE
KVGRGWRLVVAIADVSHYVRPGMALDQEAYDRGNSVYFPRRVIPMLPEKLSNGICSLNPD
VERLAMVCDMNISATGSIGKYRFYPAVFRSHARLTYNQVWGWLSGQSQPENEVHQALQPH
LQNLYKLFQVLLKARKKRGAIDFETVETQMLFNAQGKIENIVPVVRNDAHRLIEECMLAA
NVCASGFLHEHKQACLYRVHQGPTPEKLENLRAFLGEFGFSLAGGDEPKAKDYAELLEKI
QGRPDTQLLQTVMLRSLRQAQYAPENLGHFGLAYEAYTHFTSPIRRYPDLLVHRAIKAVL
AGETYNPGKWEDIGLHCSGTERRADEATRDVDNWLKCFYMKERIGEEFEGTIAGVAAFGI
FVALDEVFVEGMVHVSELGEDYFHFEPAKHQMLGERSGKRFRLGDRLRVKLVRADLESGR
IDFILAQEKKEGPAGDDEVVTWRKNTTGKPALGAAAPQGKPRAGSGGGKPGKSAPGGKAG
GPGQGGHRGKSPAAAKTGAPKRSGKGGAKGGSKSASRGGANNGGRKGR