Protein Info for Dsui_2892 in Dechlorosoma suillum PS

Annotation: phosphoribosylformylglycinamidine synthase, single chain form

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1325 TIGR01735: phosphoribosylformylglycinamidine synthase" amino acids 6 to 1324 (1319 residues), 1921.8 bits, see alignment E=0 PF18076: FGAR-AT_N" amino acids 39 to 154 (116 residues), 126.9 bits, see alignment E=9.6e-41 PF18072: FGAR-AT_linker" amino acids 176 to 224 (49 residues), 80.6 bits, see alignment (E = 2.5e-26) PF02769: AIRS_C" amino acids 432 to 599 (168 residues), 108.4 bits, see alignment E=1e-34 amino acids 847 to 1000 (154 residues), 57 bits, see alignment E=6.9e-19 PF22689: FGAR-AT_PurM_N-like" amino acids 658 to 815 (158 residues), 263.4 bits, see alignment E=1.6e-82 PF13507: GATase_5" amino acids 1073 to 1324 (252 residues), 362.2 bits, see alignment E=3.1e-112

Best Hits

Predicted SEED Role

"Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)" in subsystem De Novo Purine Biosynthesis (EC 6.3.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QGB0 at UniProt or InterPro

Protein Sequence (1325 amino acids)

>Dsui_2892 phosphoribosylformylglycinamidine synthase, single chain form (Dechlorosoma suillum PS)
MADIIFLRGAPAFSAFRLQRLQARLSAAVPAVAGVEADYWHFVQLDQPLADDARGQLARL
LEERHGEERGDDLELFLVTPRIGTISPWSSKATDIAINAGLAAVERIERGIAYWVRTPGG
RSLSAEERAAVAAQLHDRMTESVMADFDETAGLFRHFEAQRLSRVDLLAGGRPALVAANT
DLGLALSEDEIDYLLDIYQKAGRNPTDVELMMFAQANSEHCRHKIFNAAWVVDGEARDET
LFGMIKATHKANPQGTVMAYADNASIIEGAKVPRFYPQADGSYAYKEELTHILTKVETHN
HPTAISPFPGASTGSGGEIRDEGATGRGSKPKAGLCGFSVSNLFVPGAERPWETSIGKPS
RIASALSIMLEGPIGAAAFNNEFGRPNLTGYFRTYEENVGPEVRGYHKPIMIAGGLGNIE
DGQSFKAEVFPAGTLLVQLGGPGMLIGLGGGAASSMATGANNEDLDFASVQRGNPEIQRR
AQEVIDRCWQMGVPKNDIAAPGDGNPILSIHDVGAGGLSNAFPELAHSGQCGATFDLRAV
PIEEPGMSPAEIWSNESQERYVLALPPSRLEEFKALCERERCPFAVVGVTTADGRLKVTD
AKLGEDPVDMDMEALLGKPPRMTREAVHQAPAAVPFAADSINLKDAGYRVLQLPSVADKT
FLITIGDRSVGGMTARDQMVGPWQVPVADVAVTLMGYQGYQGEAFAMGERTPLAVLDAPA
SGRMAVGEAVTNLAAAPINKLSDVKLSANWMAAAGYPGEDARLFDTVKATSEVCQALGLS
IPVGKDSLSMRTAWEEGGEKKQVVSPLSLIVTGFAHSPDVRRTLTPVLQLDQGETELLLL
DLSAGKNRLGGSALAQVYNATGEQVPDLDEPKLLAAFFAVVQQLNQDGLLLAYHDRSDGG
LFAAACEMAFASRCGITINADILAYDPLQNDVDGAEKRPDLLEGRSMELLVKALFNEELG
ALVQIRRADREKITAILRQAGLGQCYSLVGYPNDRDQVRVFRNAKPLFSESRVDLQRAWS
ETSYKLQSLRDNPDCAQQEFDRILDTQDPGLSASLTFDIAEDVAAPFINSGAKPKMAILR
EQGVNSHYEMAAAFDRAGFHSVDVHMSDILAGRVSLQDFKGAVACGGFSYGDVLGAGQGW
AKTILFNGKARDEFSAFFQRPDTFALGVCNGCQMMSALKELVPGAEHWPALQRNIVEQFE
ARFVMAEVTESPSLFFAGMAGSRMPIVVSHGEGRAEFANAQDQAKALVALRYVDNKGTPT
EVYPYNPNGSPAGVTGFTTADGRFTIMMPHPERVFRSVQMSWHPSAWGEDSPWMRMFRNA
RRWVG