Protein Info for Dsui_2770 in Dechlorosoma suillum PS

Annotation: penicillin-binding protein 1C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 756 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details transmembrane" amino acids 449 to 467 (19 residues), see Phobius details TIGR02073: penicillin-binding protein 1C" amino acids 43 to 657 (615 residues), 602.7 bits, see alignment E=6.2e-185 PF00912: Transgly" amino acids 59 to 235 (177 residues), 149.6 bits, see alignment E=9.6e-48 PF00905: Transpeptidase" amino acids 316 to 604 (289 residues), 58.5 bits, see alignment E=9.9e-20 PF06832: BiPBP_C" amino acids 668 to 736 (69 residues), 58 bits, see alignment E=1.1e-19

Best Hits

Predicted SEED Role

"Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)" in subsystem Peptidoglycan Biosynthesis or Type IV pilus (EC 2.4.1.129, EC 3.4.-.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129, 3.4.-.-

Use Curated BLAST to search for 2.4.1.129 or 3.4.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QQ10 at UniProt or InterPro

Protein Sequence (756 amino acids)

>Dsui_2770 penicillin-binding protein 1C (Dechlorosoma suillum PS)
MPRSSGFGEPRPPLRRRALLPTLALLLGLAAPAAQALPDYAQVRREYRASDATLLARDGQ
VLQSLRLDRNVRRRAWTPLAEISPALVRAVIVSEDRRFMEHDGVDWRAAGKAAWSNFWGS
RTRGASTLTMQLAGLLEEDGQRRGRRSFLDKLGQSMAAGRLERTWNKRQIIEAYLNLVPF
RGELQGVGAMSQELFGKWPHGLDERESALAAALLRSPNAAPAVVARRACRLLAEMGREQE
CSDAQAFAAYVDYALSGAQRTPQAPAPQLAPHLARKLLEHPGQALRSSLDGDLQQFASHA
LRRHLHALRQQNVEDGAVLVLDNASGEILAWVGSSGDLSEAAEVDGVTALRQAGSTLKPF
LYALAFEQRALTPASLIEDAPLALDTGNGLYAPQNYEPHYQGWVSVRRALAGSLNVPAVR
TLVRLGPEPFRRKLLQAGLSSLNQDGDWYGYSLALGSADISLLMLANGYRSLANGGRWSP
LRAVPATAAGSNGKAQPIPCRREGCAGVFSDAPRPAFTAAAAFLVGDILADRNARASTFG
LESWLATPYWSAVKTGTSKDMRDNWCAGYSRRYTVAVWVGNAGGSPMHDVSGISGAAPVW
REVMDWLHRGDPARARPPQSSRPPPTPAGVVRQSIRFEPAREPARQEWFLAGTEQTVIRQ
AGGQALGRIAYPADGTILALDPDIPPNLQRIELRLSGPAAPGWHWQLDGKRLAAAQPAPH
WLPQPGRHRLQLVDARQRVIDEAAFEVRALKGKSRR