Protein Info for Dsui_2750 in Dechlorosoma suillum PS

Annotation: cyanophycin synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 861 TIGR02068: cyanophycin synthetase" amino acids 2 to 859 (858 residues), 1207.9 bits, see alignment E=0 PF18921: Cyanophycin_syn" amino acids 69 to 128 (60 residues), 40.6 bits, see alignment 1.1e-13 PF08443: RimK" amino acids 206 to 309 (104 residues), 31.7 bits, see alignment E=5.7e-11 PF02786: CPSase_L_D2" amino acids 208 to 290 (83 residues), 30.8 bits, see alignment E=1.1e-10 PF01071: GARS_A" amino acids 208 to 299 (92 residues), 27.4 bits, see alignment E=1.5e-09 PF13549: ATP-grasp_5" amino acids 210 to 274 (65 residues), 34.7 bits, see alignment 5.9e-12 PF07478: Dala_Dala_lig_C" amino acids 237 to 302 (66 residues), 26.5 bits, see alignment 2.2e-09 PF08245: Mur_ligase_M" amino acids 479 to 691 (213 residues), 79.1 bits, see alignment E=2.3e-25 PF02875: Mur_ligase_C" amino acids 716 to 794 (79 residues), 47.7 bits, see alignment E=7.9e-16

Best Hits

Swiss-Prot: 41% identical to CPHA_ANAVT: Cyanophycin synthetase (cphA) from Anabaena variabilis (strain ATCC 29413 / PCC 7937)

KEGG orthology group: K03802, cyanophycin synthetase [EC: 6.-.-.-] (inferred from 70% identity to bav:BAV1232)

MetaCyc: 44% identical to cyanophycin synthase monomer (Thermosynechococcus vestitus BP-1)
Cyanophycin synthase (L-arginine-adding). [EC: 6.3.2.30]; Cyanophycin synthase (L-aspartate-adding). [EC: 6.3.2.30, 6.3.2.29]

Predicted SEED Role

"Cyanophycin synthase (EC 6.3.2.29)(EC 6.3.2.30)" in subsystem Cyanophycin Metabolism (EC 6.3.2.29, EC 6.3.2.30)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.-.-.-, 6.3.2.29, 6.3.2.30

Use Curated BLAST to search for 6.-.-.- or 6.3.2.29 or 6.3.2.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QPZ0 at UniProt or InterPro

Protein Sequence (861 amino acids)

>Dsui_2750 cyanophycin synthetase (Dechlorosoma suillum PS)
MEVSRIRALRGPNLWSRHTSIEAIVTCSEAERFSPASSALLESFLDRLLERFPEIGLVMP
AGAAALPSVAHALQFAALGLQASAGCPVTFSRTSETLDPGVYQVVVEYTEEPVGRLAFDL
AVSLCQAALENTPFDLDNVLARLRELDEDVRLGPSTGSIVDAAIARNIPFRRLTEGSLVQ
FGWGSKQRRIQAAEMDCTSAIAESIAQDKELTKELLRAAGVPVPWGRTVADADDAWAAAQ
EIGLPVVVKPRDGNQGKGVAVNLKSEAEVRQAFDVASEFRDDVMVERYLPGQDFRVLVVG
KQLVAAARRDPPQVIGDGVHTIRQLVDQVNADPRRGEGHATSLTKIRFDEIALATLARQN
YNADSVPPRGARVPLRNNANLSTGGSATDVTDDVHPELAAKAVAAAQMVGLDICGVDVVC
ETVQRPLEEQGGGIVEVNAAPGLRMHLQPSFGKGRAVGEAVISTMYPDGDDGRIPVVAVA
GTNGKTTTVRLISHLFTCNGQRTGMTGTDGVYIQGKRIDTGDCSGPKSARNVLLHPDVDA
AVLETARGGVLREGLGFDRCNVAVVTNIGMGDHLGLAYINTVEDLAVVKRVIVENVANNG
TAVLNATDPIVARMAESCPGSVTFFAADPHHPVMATQFAQGRRGLYVEGGDIVAAEGSTV
VHRIPLSGVPLTRNGSIGFQVENVMAATGAAWAIGISWEVIRQGLATFVSDASTAPGRFN
LFDYKGATLIADYGHNPDAIQALTNAIATMTAKRRSVVISGAGDRRDEDIRQQTRILGGA
FDEVILYQDACQRGRADGEVLGLLREGLQGASRTRNVEEVRGEFLAIDTALARLSPGDLC
LILVDQVDEALEHIAKRVKEA