Protein Info for Dsui_2746 in Dechlorosoma suillum PS

Annotation: ATP-binding cassette protein, ChvD family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 TIGR03719: ATP-binding cassette protein, ChvD family" amino acids 2 to 552 (551 residues), 956.3 bits, see alignment E=5.1e-292 PF00005: ABC_tran" amino acids 22 to 190 (169 residues), 97.1 bits, see alignment E=2.8e-31 amino acids 339 to 472 (134 residues), 90.2 bits, see alignment E=3.9e-29 PF12848: ABC_tran_Xtn" amino acids 229 to 305 (77 residues), 45.5 bits, see alignment E=1.4e-15

Best Hits

Swiss-Prot: 70% identical to ETTA_HAEIN: Energy-dependent translational throttle protein EttA (ettA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K06020, sulfate-transporting ATPase [EC: 3.6.3.25] (inferred from 87% identity to lhk:LHK_01088)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system ATP-binding protein" in subsystem Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.25

Use Curated BLAST to search for 3.6.3.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QPY6 at UniProt or InterPro

Protein Sequence (554 amino acids)

>Dsui_2746 ATP-binding cassette protein, ChvD family (Dechlorosoma suillum PS)
MAQYVMSMLRVSKIVPPKRQIIKDISLSFFPGAKIGLLGLNGSGKSTVLKIMAGADKEYD
GEVQWQPNLNIGYLPQEPQLDPEKTVRQEVESALGEIMGAKQRLEEVYAAYAEPDADFDK
LAEEQARCEAILAAAGSDTEAQMEIAADALRLPAWDALIKNLSGGEKRRVALCKLLLSKP
DMLLLDEPTNHLDAESVEWLEQFLCRFPGTVVAVTHDRYFLDNAAEWILELDRGQGIPWK
GNYSSWLEQKEERLEQEGRQEAARMKAMKQELEWVRQNPKGRQAKSKARIARFEELSSYE
YQKRNETQEIFIPVGERLGNEVIEFNGVSKAFGDRLLIDNLSFKIPAGAIVGIIGPNGAG
KSTLFRMITGKEAPDSGEVKIGSTVKMAFVDQSRENLSANKTVFEEIANGADILTVGKFE
MPSRAYIGRFNFKGGDQQKQVGTLSGGERGRLHLAKTLLEGGNVLLLDEPSNDLDVETLR
ALEDALLEFPGSALIISHDRWFLDRICTHILAAEGDSQWTFFDGNYQEYEADKKKRLGEE
GAKPKRIRYKPISR