Protein Info for Dsui_2736 in Dechlorosoma suillum PS
Annotation: glycine cleavage system H protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 76% identical to GCSH_DECAR: Glycine cleavage system H protein (gcvH) from Dechloromonas aromatica (strain RCB)
KEGG orthology group: K02437, glycine cleavage system H protein (inferred from 77% identity to app:CAP2UW1_1959)MetaCyc: 58% identical to glycine cleavage system H protein (Escherichia coli K-12 substr. MG1655)
Predicted SEED Role
"Glycine cleavage system H protein" in subsystem Glycine and Serine Utilization or Glycine cleavage system or Photorespiration (oxidative C2 cycle)
MetaCyc Pathways
- glycine biosynthesis II (3/3 steps found)
- glycine cleavage (3/3 steps found)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See G8QPX6 at UniProt or InterPro
Protein Sequence (128 amino acids)
>Dsui_2736 glycine cleavage system H protein (Dechlorosoma suillum PS) MSNVPADLKYTKSHEWVRLEADGSVTVGITDHAQEALGDLVFIELPEVGKTLAAGQEAAV VESVKAAADVYAPIAGSVTAVNEAVVDAPETLNQDAYAAWLFKLQPANAGDLGALLDAAA YGAVADSE