Protein Info for Dsui_2510 in Dechlorosoma suillum PS

Annotation: anaerobic dehydrogenase, typically selenocysteine-containing

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1028 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00384: Molybdopterin" amino acids 230 to 699 (470 residues), 30.1 bits, see alignment E=2.6e-11 PF01568: Molydop_binding" amino acids 904 to 972 (69 residues), 48.2 bits, see alignment 9.8e-17

Best Hits

KEGG orthology group: K08357, tetrathionate reductase subunit A (inferred from 67% identity to tbd:Tbd_1741)

Predicted SEED Role

"Tetrathionate reductase subunit A" in subsystem Tetrathionate respiration

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QN23 at UniProt or InterPro

Protein Sequence (1028 amino acids)

>Dsui_2510 anaerobic dehydrogenase, typically selenocysteine-containing (Dechlorosoma suillum PS)
MKISKRRQVLALGGLAAFAAGYSETAGRMVGKLFGHDAPKHKTAGEAPAPEFRVDRQGKI
EINAAQQVSYTTCLGCTTMCGVRVRIDRASGKVLRVSGNPYSPLSTDPHLPMKASVRESF
IAISALNGKGLDGRSTACGRGNAVAQQIDSPYRVLTPMKRVGSRNSGQWEPISFEQLIKE
VVNGGNLFGEGNVEGLGALRDLTTPIDSKQPALGPRVNQVAVLSSVNDGRENFARRFFQQ
SFGTLNFIGHGSYCGGSYRSGSGALFGDMKTMPHCKPDFANAEFVLFVGTAPGQAGNPFK
RQGTLVAKARTDGKLSYVVVDPVLTHADNRASGDRGRWLPIKPGTDGAMAMAIIRWLFEN
ERIDSKFLSFPNAALAKQNGEPSFSNASHLVVVEAKHPRERRMLRASDMGVEMPEELRYK
ELDAFVCFDQSGKPVFHDQASGPAQIFVDTVLTIGGKEVHVKSSLQLLREEAMRLELPAY
SEACGIPAETLAGLAKELSSHGKKASVIAHGGMMSGSGFYNAYALLSINALLGNINWKGG
FVANGGGFKDNGEGPRYKLDGFPGMVKTSGTPLGRNVPYEKTAEFATRKADNKPYPATAP
WFPNAPGLTTELLPGGLNGYPYALKALILWSSNPLYGIAGLHNKIAKDLADPKKIGLIVS
VDPFINESNAFADYIVPDSLMYESWGWVAAWNGVPTKAMSARWPVIAPQAAKTPEGHAIG
METFFIALAKAMKLPGFGENAISDPEGKTYALNTPEDWYLRGGANIAWLGKEPVADATAE
DIILSGVERLRPLLEKTLKPEEIAKVAFLLSRGGRYQPGKDAYDEEDPRWMRNPMKSMAH
LWNENVGASKNSLSGKRNNGCGSWIEPAFADGTPMRKVYPADKWPLQLVSYKSALQNPYS
IGATRLLGLHPENPVLIHPDDAHRLHVEMGDLVEITTPGGSLKARIMVHAGITPGVAAIE
HGFGHRELGARAHRIGRTEQPKDKRLAAGVNLNDIGLLDPTRPDKSPWVDSISGASVRNG
LPAKMQRA