Protein Info for Dsui_2498 in Dechlorosoma suillum PS

Annotation: mercuric resistance transcriptional repressor protein MerD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 121 TIGR02054: mercuric resistence transcriptional repressor protein MerD" amino acids 1 to 119 (119 residues), 208.1 bits, see alignment E=2e-66 PF13411: MerR_1" amino acids 4 to 72 (69 residues), 50.6 bits, see alignment E=8.5e-18

Best Hits

Swiss-Prot: 97% identical to MERD_PSEAI: HTH-type transcriptional regulator MerD (merD) from Pseudomonas aeruginosa

KEGG orthology group: None (inferred from 98% identity to ppw:PputW619_2337)

Predicted SEED Role

"Mercuric resistance operon coregulator" in subsystem Mercury resistance operon

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QML9 at UniProt or InterPro

Protein Sequence (121 amino acids)

>Dsui_2498 mercuric resistance transcriptional repressor protein MerD (Dechlorosoma suillum PS)
MSAYTVSRLALDAGVSVHIVRDYLLRGLLRPVACTPGGYGLFDDAALQRLCFVRAAFEAG
IGLDALARLCRALDAADGDEAAAQLAVLRQFVERRREALADLEVQLATMPTEPAQHAESL
P