Protein Info for Dsui_2466 in Dechlorosoma suillum PS

Annotation: ATP dependent DNA ligase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF14743: DNA_ligase_OB_2" amino acids 213 to 278 (66 residues), 105.3 bits, see alignment E=6.8e-35

Best Hits

KEGG orthology group: K01971, DNA ligase (ATP) [EC: 6.5.1.1] (inferred from 65% identity to dar:Daro_1235)

Predicted SEED Role

"DNA ligase (ATP) (EC 6.5.1.1)" (EC 6.5.1.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.5.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QMJ2 at UniProt or InterPro

Protein Sequence (281 amino acids)

>Dsui_2466 ATP dependent DNA ligase-like protein (Dechlorosoma suillum PS)
MIRRLLLLLLSLGWSPLWAQSPTVPPPPLLLAETYTGQEDVAAYWVSEKLDGVRAVWDGQ
VLRFRSGRPVAAPAWFVAALPATPLDGELWAGRGHFERLSATVRRELPDDAEWRQVRYMV
FELPGGEGAFSERLQRLQALVAGARVPWLQTVEQFRLANRAQLLARLEEVRRGGGEGLML
HRADAPYVTGRSEVLLKVKPWLDAEARVVAHLPGKGRYAGMLGALRVEMPDGRRFSLGTG
FSAAERRQPPPVGALITYRYRELTATGLPRFASYWRVRQDF