Protein Info for Dsui_2455 in Dechlorosoma suillum PS

Annotation: periplasmic serine protease, Do/DeqQ family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 481 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR02037: peptidase Do" amino acids 26 to 473 (448 residues), 499.5 bits, see alignment E=4.3e-154 PF00089: Trypsin" amino acids 93 to 253 (161 residues), 72.6 bits, see alignment E=1.3e-23 PF13365: Trypsin_2" amino acids 97 to 230 (134 residues), 131.9 bits, see alignment E=9.1e-42 PF00595: PDZ" amino acids 267 to 329 (63 residues), 30.2 bits, see alignment E=1.4e-10 PF13180: PDZ_2" amino acids 269 to 360 (92 residues), 63.8 bits, see alignment E=4.5e-21 PF17820: PDZ_6" amino acids 295 to 349 (55 residues), 45.5 bits, see alignment 1.6e-15

Best Hits

Swiss-Prot: 50% identical to DEGPL_HALED: Probable periplasmic serine endoprotease DegP-like (mucD) from Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)

KEGG orthology group: K01362, [EC: 3.4.21.-] (inferred from 72% identity to dar:Daro_2024)

Predicted SEED Role

"HtrA protease/chaperone protein"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QMI1 at UniProt or InterPro

Protein Sequence (481 amino acids)

>Dsui_2455 periplasmic serine protease, Do/DeqQ family (Dechlorosoma suillum PS)
MKRLVVLLYLCCLAAVAQAADSRGLPDFADLVEKYGNTVVNISTTQVVRQKRGAMPFPFD
EDDPLFDFFRRFGPSGPFGQGQPGGAVPREFESKSLGSGFIISGDGYVLTNAHVVDQADE
ITVRLTDKREFRAKVIGADKRTDVALIKIEASNLPAVRFGDPAGLRVGEWVVAIGSPFGF
DNSVTAGIVSAKGRSLPQENYVPFIQTDVAINPGNSGGPLFNMKGEVVGINSQIYSRSGG
YQGIAFAIPIDVAMDIQGQLRASGKVSRGRIGVVIQEVTKELADSFGLAKPAGAIVNAVE
PGGPAEKAGVEAGDVILRFDGKAVGASSDLPRLVGATRPGSRVSLQVWRKGAARDLTLTV
AEMPADDKADGKAAKKGKAVEPQVNRLGLVVSELSAEQRRELKVAGGLLVEDVRGAAARS
ELRPGDIILAVISKGVTSELRSTEQFNRLLAQFDKGANVTLLIRRGDMQTFVTVKGLNGG
N