Protein Info for Dsui_2379 in Dechlorosoma suillum PS

Annotation: phosphoserine phosphatase SerB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 280 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR00338: phosphoserine phosphatase SerB" amino acids 69 to 277 (209 residues), 232.8 bits, see alignment E=3.6e-73 TIGR01488: HAD phosphoserine phosphatase-like hydrolase, family IB" amino acids 74 to 245 (172 residues), 112.4 bits, see alignment E=2.4e-36 PF00702: Hydrolase" amino acids 74 to 247 (174 residues), 82 bits, see alignment E=1.2e-26 PF12710: HAD" amino acids 76 to 243 (168 residues), 83.4 bits, see alignment E=4.4e-27 PF08282: Hydrolase_3" amino acids 211 to 253 (43 residues), 35.9 bits, see alignment 1.1e-12

Best Hits

KEGG orthology group: K01079, phosphoserine phosphatase [EC: 3.1.3.3] (inferred from 86% identity to dar:Daro_1962)

Predicted SEED Role

"Phosphoserine phosphatase (EC 3.1.3.3)" in subsystem Glycine and Serine Utilization or Serine Biosynthesis (EC 3.1.3.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.3

Use Curated BLAST to search for 3.1.3.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QLU9 at UniProt or InterPro

Protein Sequence (280 amino acids)

>Dsui_2379 phosphoserine phosphatase SerB (Dechlorosoma suillum PS)
MNLIIQNGALPTFLLDRIAAATQAAAVEPRPPRVVCFRNASRTTEFDALLPLIEAEKLDW
AFVPADRKLADYGLICFDMDSTLITIECIDELADFAGKKAEVSAVTESAMRGEIDYRESL
RRRLALLAGLDARVLARVYGERLLLSEGARELLEAAQTAGLRTAILSGGFTYFTERLRIE
LGFDFATSNELEISGGKLTGKVVGDIVDAQAKAHHLNRLRDELGLEREQVIAVGDGANDL
LMMAEAGLSVAFHAKPATRAKASVAISHGGLDSLLNLFEA