Protein Info for Dsui_2375 in Dechlorosoma suillum PS

Annotation: Fe-S protein assembly chaperone HscA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 626 PF00012: HSP70" amino acids 21 to 603 (583 residues), 605.1 bits, see alignment E=1.2e-185 TIGR01991: Fe-S protein assembly chaperone HscA" amino acids 21 to 619 (599 residues), 910.9 bits, see alignment E=1.9e-278 PF06723: MreB_Mbl" amino acids 119 to 376 (258 residues), 56.8 bits, see alignment E=1.7e-19

Best Hits

Swiss-Prot: 73% identical to HSCA_RALPJ: Chaperone protein HscA homolog (hscA) from Ralstonia pickettii (strain 12J)

KEGG orthology group: K04044, molecular chaperone HscA (inferred from 77% identity to dar:Daro_1954)

Predicted SEED Role

"Chaperone protein HscA" in subsystem Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QLU5 at UniProt or InterPro

Protein Sequence (626 amino acids)

>Dsui_2375 Fe-S protein assembly chaperone HscA (Dechlorosoma suillum PS)
MALLQIAEPGQSELPHEHKLAVGIDLGTTNSLVATVRSGMAVVLNDEDGRALLPSVVRYT
PEGEVVVGIEAQAEQARDPKNTIVSVKRFMGRGLEDIGHVESAPYDFQVAPGMVRLKTRA
GVKSPVEVSADILKVLRTRAEAALGGELVGAVITVPAYFDDAQRQATKDAARLAGLNVLR
LLNEPTAAAIAYGLDNGSEGIYAVYDLGGGTFDISILRLSKGVFEVMSTGGDSALGGDDF
DQRILCWISETAKLAPLAAMDARLLLTKAREAKEYLTGHNEAPITAKLTSGELVNLKLSA
EVFNDITQTLVAKTLQPCKKALRDAGLRPTDVKGVVMVGGATRIPAIQKAVGEFFRQEPL
TNLDPDKVVAIGAATQANLLAGNRNPGDDWLLLDVIPLSLGLETMGGLTEKVIPRNSTIP
VARAQEFTTFKDGQTAMAIHVVQGERELVSDCRSLARFELRGIPPMVAGAPRIRVTFQVD
ADGLLSVTAREQTSGVEASVAVKPSYGLTDDEITGMLQSSLEHAKDDAFRRALQEARVEA
DRLLEATEAALKEDPHLLDAGERARVDVALEKLRTVIQGEDRHAINHGMDLLALETNEFA
ARRMDQSIKRALAGKRVDDVKIGEEE