Protein Info for Dsui_2223 in Dechlorosoma suillum PS

Annotation: putative ATP-dependent protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 841 PF20437: LonC_helical" amino acids 95 to 128 (34 residues), 64.8 bits, see alignment (E = 1.1e-21) PF13654: AAA_32" amino acids 326 to 457 (132 residues), 171.8 bits, see alignment E=1.4e-54 PF20436: LonB_AAA-LID" amino acids 486 to 549 (64 residues), 59.4 bits, see alignment 5.9e-20 PF05362: Lon_C" amino acids 659 to 762 (104 residues), 32.4 bits, see alignment E=1.4e-11

Best Hits

KEGG orthology group: None (inferred from 56% identity to tmz:Tmz1t_1417)

Predicted SEED Role

"ATP-dependent protease La (EC 3.4.21.53) Type II" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent (EC 3.4.21.53)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.53

Use Curated BLAST to search for 3.4.21.53

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QKA3 at UniProt or InterPro

Protein Sequence (841 amino acids)

>Dsui_2223 putative ATP-dependent protease (Dechlorosoma suillum PS)
MTDFRQHPCRLPPERLFTPCSESLLEFATTAELDDLAEEFAHPRAVEALSFGLDIPRHGY
NLFVLGEPGSGRHALVHRVLDTQFRHRGNGDAAWDWCYVHNFQEPTRPRLLRLPAGRGSK
LREDMQNFVSGLAPALTAAFESDDYRRRLNALESEAKKREDTALRTLGREAMSKGVALLS
TEEGFTFVPAKSEDETMSEEEYDALPKERQEELDAIIESYEPRLQDLVSQFPRWQRELQA
KVKDISREALRLAVGHEIEELKPAYADLAEVSAFLDAVLHDVVETGDNLRESQKGEGEME
TLLFSGSISLQRYLVNLLVDNSGTSGRPVVCESLPTFQNLLGRVEHTAHMGMWVSNFTLI
RAGALHRANGGALVLDAGKLLTQPYAWEGLKRALQAERLRLESPEDLFGLQSTQQLEPEP
MPLDVKVVLVGDRNTYYLLSEMDPEFGALFKVAADLENDVVRGPENALLYARLLATLARR
DQLRALTRAATAWTIERAARLAEDSRKLTTRTRVLADLLREADWMAEKDGAPDIDRQHLE
RALAAQVRRADRVRERQQEAILNGEFMIATEGMEIGQINGLAAIDMGELTFAHPMRVTAA
VRMGDGDVMDIERETELGGPLHSKGMLILSGFLSNRFGRLVPLSVNASLVFEQSYGEVDG
DSASLAELCALLSAIGMLPLHQSLAMTGSLNQLGQVQPIGAVNEKIEGFFDICQARGLTG
KQGVIIPAANVSHLMLRADVVAAVRRGDFHVFAVRHVDEAMALLTGLPAGTPDAKGEVAP
DSVSGKVATQLMELAQQRHGPPEKPKAPRRSKAKESPAKPKPGKEPVEDVAGHGERGAGE
A