Protein Info for Dsui_2202 in Dechlorosoma suillum PS

Annotation: parvulin-like peptidyl-prolyl isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF13624: SurA_N_3" amino acids 1 to 161 (161 residues), 166.8 bits, see alignment E=9.2e-53 PF13623: SurA_N_2" amino acids 4 to 138 (135 residues), 106.6 bits, see alignment E=2.6e-34 PF13145: Rotamase_2" amino acids 245 to 376 (132 residues), 76.5 bits, see alignment E=7.9e-25 PF13616: Rotamase_3" amino acids 261 to 362 (102 residues), 107.8 bits, see alignment E=1.2e-34 PF00639: Rotamase" amino acids 271 to 361 (91 residues), 90.7 bits, see alignment E=2.5e-29

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 58% identity to dar:Daro_1933)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QJU1 at UniProt or InterPro

Protein Sequence (630 amino acids)

>Dsui_2202 parvulin-like peptidyl-prolyl isomerase (Dechlorosoma suillum PS)
MFDAVRNNKRIVQVFLGLITLPFAFWGVESYIRNAGDSRDVATVGGTPITLQQYQQAWRN
QQERLRGALGPNYNPALMESPEARLAVVNSLVDQRVLLLEANKRRLMASDDLLRDVISKI
PALQEDGKFSAARYETALKAQGLTQTGFEAQLRQDLTLQQLVGSVSDTGMVAAAAAEAML
RIQAEERQVAELRIVPEQFAAQAKPSAEAMQKFYEENRASFEIPEQVRAEFVQLSVDALL
AQLVVTPEEIKSWYEGHKDRYQQSEERRASHILIPSGSDVAQAKSKAEAVLKEVQQNPAK
FADIAKRESKDPGSASKGGDLGFFGKGSMVKPFEDAVFSQKEGELSGLVQSDFGFHIIKV
TGIKGGKLKTLDEVKPEIEAELKRQAASRKFAEAAEAFSNTVYEQSDSLKPAADRFKLPL
QQTGWFSRRGGQNAGVLGNEKALAVLFSEDVLKNKRNTEAVEIAPNTLVAARIVEHKPAS
LKPFDTVKGQIEEILKIQESNALAKKAGEEKLAQLKAGEDKLGWALVKNVSRMEGSRQVP
PAALQAIFKTDAGKLPAYTGVEFPNNGGYVLYKIMKVSQPSSLDEGKRKVLQKEYTSLVA
QEDFAAYLAGLRARYKVEVNKAALEDNKDR