Protein Info for Dsui_2066 in Dechlorosoma suillum PS

Annotation: ABC-type metal ion transport system, periplasmic component/surface antigen

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF03180: Lipoprotein_9" amino acids 29 to 263 (235 residues), 264.2 bits, see alignment E=4.2e-83

Best Hits

Swiss-Prot: 37% identical to METQ_VIBCH: Probable D-methionine-binding lipoprotein MetQ (metQ) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02073, D-methionine transport system substrate-binding protein (inferred from 67% identity to vpe:Varpa_4374)

Predicted SEED Role

"Methionine ABC transporter substrate-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation or Staphylococcal pathogenicity islands SaPI

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QIM5 at UniProt or InterPro

Protein Sequence (267 amino acids)

>Dsui_2066 ABC-type metal ion transport system, periplasmic component/surface antigen (Dechlorosoma suillum PS)
MKLIRSLLVAGLALGLAAAPAFAQEKKNLTIGATAGPNFDQVKLGIKPILEKKGYSVKLV
EFNDYVQPNLALAQGSLDANVFQHVIYLKKFSADKGLNLTDVVKVPVAPMGLYSKKAKSL
KDVKDGDRVTLPNDPSNLARALHFLEQNGLIKVKAGIDALKATEKDVAENPRKLQLTPIE
AAQLPRTLDDAGLVVVPGNFAIASGLKLSEAISLEKTPDHYLNVVAVKTEDQNKAWAQDI
VAAFKSAEFKAVLDKHFQGYARPNYWQ