Protein Info for Dsui_1891 in Dechlorosoma suillum PS

Annotation: enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 389 PF13378: MR_MLE_C" amino acids 165 to 376 (212 residues), 125 bits, see alignment E=1.9e-40

Best Hits

Swiss-Prot: 76% identical to TARD_BRADU: D(-)-tartrate dehydratase (tarD) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: None (inferred from 87% identity to azo:azo1246)

MetaCyc: 76% identical to D-tartrate dehydratase (Bradyrhizobium diazoefficiens)
D(-)-tartrate dehydratase. [EC: 4.2.1.81]

Predicted SEED Role

"mandelate racemase/muconate lactonizing enzyme family protein" in subsystem Catechol branch of beta-ketoadipate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.81

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QHC1 at UniProt or InterPro

Protein Sequence (389 amino acids)

>Dsui_1891 enolase superfamily enzyme related to L-alanine-DL-glutamate epimerase (Dechlorosoma suillum PS)
MRIVDIREVTRPISSPIRNAYIDFSKMTLSLVAVVTDVIRDGKPVVGYGFNSNGRYGQGS
LIRERFRPRILEAAPDSLLDESGNNLDPHKVWACMMNNEKPGGHGERSVAVGTLDMAIWD
AVAKIEGKPLYQLLAERYGNGTPKREVFVYAAGGYYWPGQDLQALKNEMQGYLDRGYKVV
KKKIGGGTLADDLKRIEAVLSILPAGCKLAVDANGRFDLPTAIDYAKALSQYDLFWYEEA
GDPLDYALQAELANHYAGPMATGENLFSMQDARNLIRYGGMRADRDWLQFDCALSYGLVE
YLRTLDMLKEHGWSPSRCIPHGGHQMSLAIAAGLGLGGNESYPDLFQPFGGFPDGVQVKD
GIVTLPELPGIGFEGKADLYAEMKALGEA