Protein Info for Dsui_1715 in Dechlorosoma suillum PS

Annotation: response regulator with CheY-like receiver domain and winged-helix DNA-binding domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 584 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00072: Response_reg" amino acids 15 to 125 (111 residues), 91.2 bits, see alignment E=7.6e-30 PF07228: SpoIIE" amino acids 200 to 389 (190 residues), 118.2 bits, see alignment E=6.9e-38 PF13581: HATPase_c_2" amino acids 437 to 569 (133 residues), 31.6 bits, see alignment E=2.3e-11

Best Hits

Predicted SEED Role

"Serine phosphatase RsbU, regulator of sigma subunit" in subsystem SigmaB stress responce regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QG27 at UniProt or InterPro

Protein Sequence (584 amino acids)

>Dsui_1715 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain (Dechlorosoma suillum PS)
MKAVAGPIAVPALAILLVEDDPLDAELTQLELERFGHRVSVARSGEEALALYASFRPDLV
VTDISLPGMCGCELTRQLKSREHPHWLPVLFMSGAQSESSLVEAYQAGADDFIHKPISRP
VLQAKLGVFQQRLHLQREAQARERLLQRYRDQVEEEKSVALHLMHRLVNAELLGDLAVSH
WMRPAETYSGDLIAAARTPGGILHVLLADATGHGLAASLAVMPVTQPFYRMTEKGFGIDA
IAREMNRKVAELLPVGRFVAATLAAVDSASGSIQVWNGGNPPPFLVNSQGLLSSITFAKA
HLPLGILADEDFDASTEVHFIEEPKQLVIYSDGVVEAENGSGTPFGRERLLNALLSQERE
ERLAGVVGALDAHLAGRGAQDDLSLMLVHCYHQTARSPRIGGGTPRVLRHSGSWQVTMSL
SADDIRNLDPVPTLMGVLSQFNRDKDHGSHIFLILSELYNNALDHGVLGLDSGLKAQSQG
FERYLEERGRRLAALRDGTVDLEVTQQHRGGRTELVMRVRDSGPGFDHAAFMASLESECS
GKVPHGRGIRLVHSLCSALHYCAPGNEVIAYYDMTDFGYAGDRQ