Protein Info for Dsui_1622 in Dechlorosoma suillum PS

Annotation: excinuclease ABC, A subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 939 TIGR00630: excinuclease ABC subunit A" amino acids 4 to 921 (918 residues), 1500.8 bits, see alignment E=0 PF17760: UvrA_inter" amino acids 130 to 235 (106 residues), 133.4 bits, see alignment E=1e-42 PF17755: UvrA_DNA-bind" amino acids 288 to 397 (110 residues), 122.6 bits, see alignment E=3.4e-39

Best Hits

Swiss-Prot: 71% identical to UVRA_ECO57: UvrABC system protein A (uvrA) from Escherichia coli O157:H7

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 70% identity to abo:ABO_0427)

MetaCyc: 71% identical to UvrABC excision nuclease subunit A (Escherichia coli K-12 substr. MG1655)
3.1.25.-

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QPV1 at UniProt or InterPro

Protein Sequence (939 amino acids)

>Dsui_1622 excinuclease ABC, A subunit (Dechlorosoma suillum PS)
MDEIKIRGARTHNLKNISLDLPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAY
ARQFLQLMEKPDVDLIEGLSPAISIEQKATSHNPRSTVGTVTEIHDYLRLLYARAGTPYC
PEHGEPLEAQTVSQMVDHVLALPEETKLMILAPVVANRKGEQLDLFTELRAQGFVRLRVD
GTIYEIDNLPKLAKSQKHNIDVVVDRLKVREDMRQRLAESFETALRHADGRAIALEMESN
QEHLFSAKFACPICSYALQELEPRLFSFNNPMGACPKCDGLGVIQFFDPKRVVAHPDLSL
AAGAIRGWDKRNQFYFQMIGSLAEYYGFSVDTPFSELTDEVKQVLLYGSDKDLVPFQYMN
ERGKLVLKEHAFEGIIPNLERRYKETDSLAVREELAKYISNTTCPTCEGTRLRQEARHVK
VGSKTLHEISHLPLAEARDYFETIQLTGHKAQVAEKILKEITSRLQFLINVGLDYLSLDR
SAETLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLQTLRQLRDIGNTVI
VVEHDEDAIRTADYVVDIGPGAGVHGGAIVAEGTPQQVTDNPASMTGDYLSGRKKIEVPK
KRRQADPEKKLQVIGAKGNNLKDVSLELPVGLMTCITGVSGSGKSTLINDTLYTAAAKHL
YGSTAEPAEHEEIIGLDHFDKVINVDQSPIGRTPRSNPATYTGLLTPIRELFAGVPEARS
RGYGPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDVCHGKRYNRETLEVHYKGK
SIYDVLQMTVEQAREFFDPVPVVARKLQTLVDVGLSYITLGQSATTLSGGEAQRVKLALE
LSKRDTGRTLYILDEPTTGLHFADIEMLLKVLHRLADHGNTVVVIEHNLDVIKTADWLVD
LGPEGGGGGGRIIAAGAPEAVVKVGESHTGRFLKPLLSR