Protein Info for Dsui_1619 in Dechlorosoma suillum PS

Annotation: putative membrane-associated, metal-dependent hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 583 transmembrane" amino acids 16 to 36 (21 residues), see Phobius details amino acids 48 to 69 (22 residues), see Phobius details amino acids 88 to 109 (22 residues), see Phobius details amino acids 120 to 141 (22 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details amino acids 197 to 218 (22 residues), see Phobius details PF08019: EptA_B_N" amino acids 101 to 249 (149 residues), 152.8 bits, see alignment E=6.9e-49 PF00884: Sulfatase" amino acids 278 to 566 (289 residues), 236 bits, see alignment E=6.1e-74

Best Hits

KEGG orthology group: K03760, phosphoethanolamine transferase (inferred from 57% identity to dia:Dtpsy_2213)

Predicted SEED Role

"Phosphoethanolamine transferase EptA specific for the 1 phosphate group of core-lipid A" in subsystem Lipid A modifications

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QPU8 at UniProt or InterPro

Protein Sequence (583 amino acids)

>Dsui_1619 putative membrane-associated, metal-dependent hydrolase (Dechlorosoma suillum PS)
MAVFAPAPALVANPSGLILAGLTLVNLLLAFAFWFYQGSRQGLSRWRHWQPAVGGTTLAL
LGSVYFSLAGNRLFWEAAMAGRDGGQWSTWGFAAALFIFLSAIHFVLLAPLMGRRTAKPV
LALLLVVVGCASFYMEKYGIYLDPSMLRNVLKTDVKEAGELLTWSLLPHLALVVGLPLLL
LSRVRLPEAGLGRTLAIRAGSLLLALVLGGGAVFLVFQDFASLMRNHKEIRYLITPANLV
YSLSRVAKAEAAQGPRQPIGTDAALAAAWKGRSKPALFVIVVGETARAANWGLNGYERQT
TPELAKLDVINFPQVSSCGTNTEVSVPCIFAPVGRRDYDEEKIRGSESLLHVLDRAGFKV
LWRDNQSGCKGVCEGLPNDSLTNAAIPGLCDGERCLDEVLLHNLDKVLADDKGNRVLVLH
QLGNHGPAYHKRYPEAYRRYAPTCDSSDLRQCSREQIVNSYDNALLYTDHMLAKTIDFLK
SQDKDYDTGLMYFSDHGESLGENNLFLHGMPYSIAPQEQTRVPMVMWLSRNFAQDFKVNV
SCLKARAAQPASHDNIFHSVLGLLDVSTSIYDAKLDLAAGCRS