Protein Info for Dsui_1582 in Dechlorosoma suillum PS

Annotation: Fe-S oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02754: CCG
  • amino acids 3 to 84 (82 residues), 60.9 bits, E=5.3e-21
  • amino acids 132 to 216 (85 residues), 54.8 bits, E=4.1e-19

Best Hits

Swiss-Prot: 50% identical to LUTA_BACHD: Lactate utilization protein A (lutA) from Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)

KEGG orthology group: None (inferred from 68% identity to eba:ebA4050)

MetaCyc: 48% identical to iron-sulfur oxidase subunit used in L-lactate utilization (Bacillus subtilis subtilis 168)
L-lactate dehydrogenase. [EC: 1.1.1.27]

Predicted SEED Role

"Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE" in subsystem Lactate utilization

MetaCyc Pathways

• superpathway of anaerobic sucrose degradation (16/19 steps found)
• Bifidobacterium shunt (13/15 steps found)
• homolactic fermentation (10/12 steps found)
• pyruvate fermentation to acetate and (S)-lactate I (4/4 steps found)
• hexitol fermentation to lactate, formate, ethanol and acetate (14/19 steps found)
• pyruvate fermentation to (S)-lactate (1/1 steps found)
• pyruvate fermentation to acetate and lactate II (3/4 steps found)
• heterolactic fermentation (11/18 steps found)
• superpathway of glucose and xylose degradation (10/17 steps found)
• (S)-lactate fermentation to propanoate, acetate and hydrogen (7/13 steps found)

KEGG Metabolic Maps

• Cysteine metabolism
• Glycolysis / Gluconeogenesis
• Propanoate metabolism
• Pyruvate metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.27

Sequence Analysis Tools

See G8QPR2 at UniProt or InterPro

Protein Sequence (242 amino acids)

>Dsui_1582 Fe-S oxidoreductase (Dechlorosoma suillum PS)
MRVALFVTCLADLMRPNVAFAALKLLKLAGCTVEVPETQTCCGQPAYNSGDRATALTLAR
KVIDEFEGYEYVVLPSGSCAGMIRAHYEELCKDDPALLARAKKLAACTYELTDFLVNVAK
LESVPGDFAGSITYHDSCSGLRELGIKQQPRQLLGKMGQVEIKEMSEAETCCGFGGTFSL
KFGDISTKLADNKCENACATGADAIVGGDLGCLLNIEGRLRRKGDRKTQVLHVAEVLAGK
LD