Protein Info for Dsui_1561 in Dechlorosoma suillum PS

Annotation: transketolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 661 PF00456: Transketolase_N" amino acids 7 to 333 (327 residues), 551.1 bits, see alignment E=1.6e-169 TIGR00232: transketolase" amino acids 7 to 660 (654 residues), 999 bits, see alignment E=4.8e-305 PF02779: Transket_pyr" amino acids 353 to 523 (171 residues), 197.3 bits, see alignment E=3.4e-62 PF02780: Transketolase_C" amino acids 546 to 652 (107 residues), 50.4 bits, see alignment E=4.2e-17

Best Hits

Swiss-Prot: 69% identical to TKT1_VIBCH: Transketolase 1 (tkt1) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K00615, transketolase [EC: 2.2.1.1] (inferred from 79% identity to dar:Daro_3591)

MetaCyc: 67% identical to transketolase 1 (Escherichia coli K-12 substr. MG1655)
Transketolase. [EC: 2.2.1.1]; 2.2.1.1 [EC: 2.2.1.1]

Predicted SEED Role

"Transketolase (EC 2.2.1.1)" in subsystem Calvin-Benson cycle or Pentose phosphate pathway (EC 2.2.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.2.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QPP1 at UniProt or InterPro

Protein Sequence (661 amino acids)

>Dsui_1561 transketolase (Dechlorosoma suillum PS)
MQFNPLTSAIRALAMDAVQKANSGHPGMPMGMAEIAEVLWRRHMKHNPANPRWADRDRFV
LSNGHGSMLLYSLLHLTGYDVSIDDLKNFRQLHSKTPGHPEVGYTPGIETTTGPLGQGIT
NAVGLALAEKILAAEFNQPGHDIVDHHTYVFLGDGCLMEGVSHEACSLAGTLGLGKLIAF
YDDNGISIDGHVEGWFTDDTPKRFEAYGWQVIPNVDGHNATAIEAALLQAKAEGNKPTLI
CCKTKIGMGSPNKADSHDVHGAPLGDAEIAATRAAIGWNHAPFEIPADVYAAWDGKAKGQ
TAEGQWNERFAAYAAAFPAQAAEFQRRMAGKLPANWQQTVDAYIADTAAKAENIATRKAS
QNAIAALVPNLPEVVGGSADLAGSNLTLWKAAKGVTRKDGGNYVYYGVREFGMTAIANGL
ALHGGLIPYTATFLVFSDYARNAIRMAALMKQRQIMVYTHDSIGLGEDGPTHQPVEHVPS
LRLIPNLDVWRPADSTETAVAWANAVERHDGPSVLALSRQNLPNVTAGISAETIRRGGYV
LSEAKGEAQVVLIATGSEIKLALDAQKALGDEGIAARVVSMPCVEAFERQDAAYREQVLG
TCRKRVAIEAAHSGLWHKYVGRHGAVVSIDRFGESAPAGKLFEMFGFTVANVVKTVKEVL
E