Protein Info for Dsui_1558 in Dechlorosoma suillum PS

Annotation: glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 PF00044: Gp_dh_N" amino acids 9 to 110 (102 residues), 100.9 bits, see alignment E=4.5e-33 PF02800: Gp_dh_C" amino acids 168 to 323 (156 residues), 154.4 bits, see alignment E=2e-49

Best Hits

Swiss-Prot: 51% identical to E4PD_SHEON: D-erythrose-4-phosphate dehydrogenase (epd) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K03472, D-erythrose 4-phosphate dehydrogenase [EC: 1.2.1.72] (inferred from 74% identity to azo:azo2418)

MetaCyc: 48% identical to D-erythrose-4-phosphate dehydrogenase (Escherichia coli K-12 substr. MG1655)
Erythrose-4-phosphate dehydrogenase. [EC: 1.2.1.72]

Predicted SEED Role

"D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72)" in subsystem Pyridoxin (Vitamin B6) Biosynthesis (EC 1.2.1.72)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QP94 at UniProt or InterPro

Protein Sequence (348 amino acids)

>Dsui_1558 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase (Dechlorosoma suillum PS)
MSGSLPPLRLAINGYGRIGRCFLRALHERGLAERFQVVAINEPANSESIAYLTCFDSTHG
RFPAPVELQDGTLVIDGRSIQLTHADTPEGVDWRSLKVDLLVECSGQYSNRAGLRRFLEA
GCPRVLLSHPANSAADVDATVVYGLNHGRLNGDERIVSNASCTTNAVVPVLELLDRELGL
EQVLLTTLHSVMNDQPLVDGYHHSDLRRTRSAMQSMIPVSTGLARGVERLLPSLKGKVLA
KAIRVPTLNVSAIDLTVTLAQDADVAGLNALLQIASNGPWKGVLTTSAAPHASIDFNHDP
HSAIVDLSQTRAGGARLFNLFIWFDNEWGFVNRMVDVAQRWHAGWSQS