Protein Info for Dsui_1399 in Dechlorosoma suillum PS

Annotation: conserved hypothetical integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 transmembrane" amino acids 15 to 32 (18 residues), see Phobius details amino acids 47 to 73 (27 residues), see Phobius details amino acids 85 to 108 (24 residues), see Phobius details amino acids 154 to 178 (25 residues), see Phobius details amino acids 198 to 218 (21 residues), see Phobius details amino acids 237 to 257 (21 residues), see Phobius details TIGR00056: ABC transport permease subunit" amino acids 7 to 259 (253 residues), 279 bits, see alignment E=2.2e-87 PF02405: MlaE" amino acids 44 to 254 (211 residues), 246.4 bits, see alignment E=1.2e-77

Best Hits

Swiss-Prot: 64% identical to MLAE_ECO57: Intermembrane phospholipid transport system permease protein MlaE (mlaE) from Escherichia coli O157:H7

KEGG orthology group: K02066, putative ABC transport system permease protein (inferred from 84% identity to eba:ebA1312)

Predicted SEED Role

"Uncharacterized ABC transporter, permease component YrbE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QN09 at UniProt or InterPro

Protein Sequence (260 amino acids)

>Dsui_1399 conserved hypothetical integral membrane protein (Dechlorosoma suillum PS)
MADLLRRLGASLVDRIWQLGFASRFFWAVLRYSGQCLTRPNLTVREVYFSGVLSLLIITV
SGLFVGMVLGLQGYETLQRFGSSEALGILVALSLVRELGPVVAALLFASRAGSSITAEIG
LMKATEQLKAMDMMAVNPLARVVAPRFWGGVISMPFLAALFSAMGVFGGWLVGVVLIGVD
DGAFWSQMQASVDFREDILNGVIKSVVFGAAVSWISVFEGYDSAPTAEGVSRAITRTVVT
SALVILALDVVLTSFMFRGA