Protein Info for Dsui_1373 in Dechlorosoma suillum PS

Annotation: ATP-dependent helicase HrpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1320 TIGR01967: RNA helicase HrpA" amino acids 28 to 1315 (1288 residues), 1611.2 bits, see alignment E=0 PF00270: DEAD" amino acids 93 to 240 (148 residues), 28.4 bits, see alignment E=4.6e-10 PF13401: AAA_22" amino acids 99 to 235 (137 residues), 28.5 bits, see alignment E=5.9e-10 PF00271: Helicase_C" amino acids 296 to 417 (122 residues), 41.1 bits, see alignment E=6.5e-14 PF21010: HA2_C" amino acids 508 to 561 (54 residues), 44.1 bits, see alignment (E = 8.9e-15) PF07717: OB_NTP_bind" amino acids 631 to 707 (77 residues), 63.8 bits, see alignment 4.9e-21 PF11898: DUF3418" amino acids 721 to 1315 (595 residues), 688.7 bits, see alignment E=2.7e-210

Best Hits

KEGG orthology group: K03578, ATP-dependent helicase HrpA [EC: 3.6.4.13] (inferred from 70% identity to app:CAP2UW1_0646)

Predicted SEED Role

"macromolecule metabolism; macromolecule synthesis, modification; dna - replication, repair, restr./modif."

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QMY3 at UniProt or InterPro

Protein Sequence (1320 amino acids)

>Dsui_1373 ATP-dependent helicase HrpA (Dechlorosoma suillum PS)
MCQNTALQFFHPPIVSLPRSAPPAFADCLTQDRPRLRALSRSAGQPGPHAEKAKADYEAL
LARSRAACAEWAGRLPKPEYAEDLPVNGRREEIKALIEHNQVVIVCGETGSGKTTQLPKI
CLELGRGAAGLIGHTQPRRLAARSVAARVAQELQTQIGAGVGVKIRFQDRSGPQSYLKLM
TDGILLAETQTDPYLNAYDTIIIDEAHERSLNIDFLLGYLKQLLAKRKDLKVIITSATID
AERFAQHFAQHGKPAPVIEVSGRLYPVEVRYRPVTPLEEDQEERDLYDAIVDAVHELGRE
GPGDVLVFLPGEREIREAAEALRKHHFPGPQPEILPLFSRLSAAEQDRVFKTGGGRRVVL
ATNVAETSLTVPGIRYVVDTGLARVKRYSYRNKVEMLQVERVSQAAARQRAGRCGRVAAG
VCIRLYDEADFNARGEFTDPEILRSSLAGVILRMKALKLTDVESFPFIEAPPPKAINDGY
SLLQELGGLDEDNRLTDVGRGLAKLPLDPRIARMIVAARDRGCLKEVLVIAAALSVQDPR
ERPQERLQAADEKHRQFADEKSEFLSWLKLWNWFEEQARHLSGRKLAEACKERFLSYLRM
REWREVYNQIHAMVTELGWRENEIPATYEPIHKALLTGLLGNIGCKSDDSSHYLGARGIR
FLIHPGSPLQKKAGKWVVCAELTETTKLYARCLARIEPEWLEEVGAHLIRKSYFDPHWEK
KAMQAVAYERSTLHGIVVNPKKRVNFGPMNPEEARLLFIRQGLVGGEINEDFVRRWPFYQ
HNQKAIRDIENLEHKQRRQDVLVDDELIFAFYDHLIPSGIYNGADFDKWRKEAERENQKL
LFLQKEDLMRHEAAGVTTDAFPPQMRLSGVDYALTYHFEPGSPRDGVTLVLPLAQLNQVP
ANRSEWLVPGLLKEKVVQLVKTLPQRIRAKLVPVPEFAEEFIAWVGNDEKRMAPGIIAPL
IDFIFESRGLNARGWAVTPDAFRPGELPAHFSMNFKLVDEHGRQLDMSRSLAQLRGEWGR
EARQEFQELHETPSEFTGLTDWTFGKLPELMEVAVGGQMVIGYPGLTEDGETVSLRVYDS
QEEALAAHRLGLSRLFQLQLKEQVKYFEKNLPGLTQMAMQFMSLGSSDDLRQQLVSVIFE
RACLVEPWPEDAESFKARCAEGKNRLGLLAQEICRLVGLVLTEWQALVKKLPAFKPFPGA
VQDIEKQIGRLIHKRFVLETPFERLQHFPRYLKAAAMRLDKLKANPARDVQLLADYSTLW
TQYERRALQLAKQGVSDPQLEQFRWLLEELRVNLFAQELKTPVPVSVKRLQKLWEGIQYG