Protein Info for Dsui_1266 in Dechlorosoma suillum PS

Annotation: transcriptional regulator NrdR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 151 TIGR00244: transcriptional regulator NrdR" amino acids 2 to 137 (136 residues), 170.1 bits, see alignment E=1.6e-54 PF22811: Zn_ribbon_NrdR" amino acids 2 to 34 (33 residues), 49.3 bits, see alignment 3.6e-17 PF03477: ATP-cone" amino acids 42 to 128 (87 residues), 72.2 bits, see alignment E=4.3e-24

Best Hits

Swiss-Prot: 72% identical to NRDR_CUPTR: Transcriptional repressor NrdR (nrdR) from Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1)

KEGG orthology group: K07738, transcriptional repressor NrdR (inferred from 83% identity to app:CAP2UW1_1499)

Predicted SEED Role

"Ribonucleotide reductase transcriptional regulator NrdR" in subsystem Ribonucleotide reduction

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QLS6 at UniProt or InterPro

Protein Sequence (151 amino acids)

>Dsui_1266 transcriptional regulator NrdR (Dechlorosoma suillum PS)
MDTTVVDTRINEDGDIVRRRRRCLNCDKRFTTYERAEIRLPQVVKKNGSRVDYNRDKLSA
SLWLALRKRPVTTEAVDGAITRIEEKLLALGEREIPSEKVGEMVMRELKKLDKIAYVRFA
SVYRNFEDVDEFSHAVREVTPGKPVRRPRDE