Protein Info for Dsui_1198 in Dechlorosoma suillum PS

Annotation: apolipoprotein N-acyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 505 transmembrane" amino acids 20 to 50 (31 residues), see Phobius details amino acids 61 to 81 (21 residues), see Phobius details amino acids 92 to 112 (21 residues), see Phobius details amino acids 130 to 153 (24 residues), see Phobius details amino acids 169 to 194 (26 residues), see Phobius details amino acids 201 to 221 (21 residues), see Phobius details amino acids 481 to 499 (19 residues), see Phobius details PF20154: LNT_N" amino acids 23 to 187 (165 residues), 136.9 bits, see alignment E=7.4e-44 TIGR00546: apolipoprotein N-acyltransferase" amino acids 67 to 452 (386 residues), 328.2 bits, see alignment E=4.1e-102 PF00795: CN_hydrolase" amino acids 228 to 468 (241 residues), 116.8 bits, see alignment E=1.1e-37

Best Hits

Swiss-Prot: 49% identical to LNT_RALSO: Apolipoprotein N-acyltransferase (lnt) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03820, apolipoprotein N-acyltransferase [EC: 2.3.1.-] (inferred from 49% identity to nmu:Nmul_A0552)

Predicted SEED Role

"Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE" in subsystem Phosphate metabolism or Copper homeostasis: copper tolerance (EC 2.3.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.-

Use Curated BLAST to search for 2.3.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QLK9 at UniProt or InterPro

Protein Sequence (505 amino acids)

>Dsui_1198 apolipoprotein N-acyltransferase (Dechlorosoma suillum PS)
MGIAAFLSPLRSDGRARLLAAGAGLLGVGAFAPFAVFWLAWLSWGALFLLVSRAPSPRAA
AWRGFAFGLAQFLGGVSWVYVSLHDVGGMPLPVAALATLALCAYMALYPMAAAWSARRLD
FSDKASWRSACLFAASWVLAEWARGWVLTGFPWLALGYSQSPPSPLAGLAPLLGVYGVSL
ASALLGAWGALAVVGRQRLPGLLVLLLLGLGAGLGLVQWTVPAGEPLRVALLQGNIPQDL
KWQPERFLDSLTTYVGLARDNPADLTVLPETAVPALYDQLPPEFIADLKALAARRGGDLL
LGVPVADESSGERRYYNSAIGFGASPQQSYSKAHLVPFGEFVPPGFRWFLDLMHMPMSDF
SSGGARQPTLALAGQQIAPNICYEDVFGGEIIHALPRATLLVNLSNTAWFGRSLAQPQHL
QIAQLRALETGRPMLRATNTGMTAVVAPDGRVQAVLPPFTRGALVAEVRGYQGLTPFART
GNTVALFLATLLLAAGALARRRETQ