Protein Info for Dsui_1171 in Dechlorosoma suillum PS

Annotation: cytochrome c-type biogenesis protein CcmE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 172 signal peptide" amino acids 1 to 45 (45 residues), see Phobius details PF03100: CcmE" amino acids 4 to 130 (127 residues), 169.6 bits, see alignment E=1.5e-54

Best Hits

Swiss-Prot: 71% identical to CCME_POLNA: Cytochrome c-type biogenesis protein CcmE (ccmE) from Polaromonas naphthalenivorans (strain CJ2)

KEGG orthology group: K02197, cytochrome c-type biogenesis protein CcmE (inferred from 74% identity to app:CAP2UW1_0724)

MetaCyc: 43% identical to periplasmic heme chaperone (Escherichia coli K-12 substr. MG1655)
RXN-21407

Predicted SEED Role

"Cytochrome c-type biogenesis protein CcmE, heme chaperone" in subsystem Biogenesis of c-type cytochromes

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QKW8 at UniProt or InterPro

Protein Sequence (172 amino acids)

>Dsui_1171 cytochrome c-type biogenesis protein CcmE (Dechlorosoma suillum PS)
MKARHKRIALIVAGLAVLGIGTALVLNAFNSNLVFFFSPTQVLAGEAPKGKTFRIGGLVK
EGSVERLADGVSVRFAVTDTDQTLPVQYKGILPDLFKEGKGVVAQGKLDDAGLFVATEVL
AKHDENYMPPEAQKAVADAHAKAGENKAAAEAGEKKAAVEAAEKAAAKTLKY