Protein Info for Dsui_1152 in Dechlorosoma suillum PS

Annotation: Ni,Fe-hydrogenase I large subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00374: NiFeSe_Hases
  • amino acids 38 to 115 (78 residues), 67.3 bits, E=6.9e-23
  • amino acids 144 to 486 (343 residues), 197.7 bits, E=2e-62

Best Hits

KEGG orthology group: None (inferred from 65% identity to azo:azo3808)

Predicted SEED Role

"Uptake hydrogenase large subunit (EC 1.12.99.6)" in subsystem Hydrogenases or Membrane-bound Ni, Fe-hydrogenase (EC 1.12.99.6)

MetaCyc Pathways

• hydrogen oxidation I (aerobic) (1/1 steps found)

KEGG Metabolic Maps

• Trinitrotoluene degradation

Isozymes

Compare fitness of predicted isozymes for: 1.12.99.6

Use Curated BLAST to search for 1.12.99.6

Sequence Analysis Tools

See G8QKU9 at UniProt or InterPro

Protein Sequence (486 amino acids)

>Dsui_1152 Ni,Fe-hydrogenase I large subunit (Dechlorosoma suillum PS)
MSKLVLGPFNRVEGDLEVSLEVSDGAVHSARVNAPLYRGFEPMLLGKAPLDALAIVPRIC
GICSVAQSAAAASALAEAMGLTPPPNGRLARNLIQAGENLADHLTHFYLFFMPDFARGSY
AAKPWFAETEGRFKAQTGRATAEMLPARAGFMRLQGYLAGKWPHTMALQPGGTTRAVLAA
EKIRLYAVLREFRAWLESTLFGDALETVAALDSADALRAWAAGRQADFPRFLALADDLGL
QQVGRAGNLFLSVGAYPGSVGSLFPAGVWDGAKGRRAELDTARIVEDLSHAWLAGDAPQA
PAQGQTRPLLEKEDAYTWCKAPRYGGQVAEVGALARQLVAGQPLAQDLVRNGQGKSAGGN
VTARIVARMLEIAALIPAMENWVQQLAPGEPFCAHGELPDTAVGVGLTEAARGSLGHWLT
VKHGAIAGYQIIAPTTWNFSPRDAAGTPGPLEQALVGLPIPKDEAAPVLVQHVVRSFDPC
MVCTVH