Protein Info for Dsui_1149 in Dechlorosoma suillum PS

Annotation: Zn-dependent protease with chaperone function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 transmembrane" amino acids 5 to 26 (22 residues), see Phobius details amino acids 38 to 59 (22 residues), see Phobius details amino acids 156 to 178 (23 residues), see Phobius details amino acids 195 to 219 (25 residues), see Phobius details PF01435: Peptidase_M48" amino acids 80 to 292 (213 residues), 137.6 bits, see alignment E=2.3e-44

Best Hits

Swiss-Prot: 70% identical to HTPX_CHLPB: Protease HtpX homolog (htpX) from Chlorobium phaeobacteroides (strain BS1)

KEGG orthology group: K03799, heat shock protein HtpX [EC: 3.4.24.-] (inferred from 77% identity to tmz:Tmz1t_0267)

Predicted SEED Role

"Probable protease htpX homolog (EC 3.4.24.-)" (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QKU6 at UniProt or InterPro

Protein Sequence (293 amino acids)

>Dsui_1149 Zn-dependent protease with chaperone function (Dechlorosoma suillum PS)
MKRVLIFLATNLAIMVVLGLVINLLGLNRFLTANGLNLPMLLGFAAVMGFGGSFISLWLS
KPMAKWSTGAQVIEQPRNPTEAWLVDTVARLAKNAGLPMPEVAIYEGEANAFATGPSRNN
SLVAVSTGLLQSMSREEVEAVLAHEVAHVANGDMVTLTLIQGVVNTFVFFLARVVGYLVD
SFLRKDNEESSGPGLGYMVTVVVCDIVFGILASMIVMYFSRQREFRADAGAARLMGNNPR
PMMAALQRLGGLSPEPLPANMAASGIAGGKGWMSLFSSHPPIEERIAALQQRG