Protein Info for Dsui_0987 in Dechlorosoma suillum PS

Annotation: Zn-dependent hydrolase, glyoxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 311 PF00753: Lactamase_B" amino acids 23 to 210 (188 residues), 88.2 bits, see alignment E=3.6e-29

Best Hits

KEGG orthology group: K01467, beta-lactamase [EC: 3.5.2.6] (inferred from 68% identity to app:CAP2UW1_4322)

Predicted SEED Role

"Beta-lactamase-like"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.6

Use Curated BLAST to search for 3.5.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QJG7 at UniProt or InterPro

Protein Sequence (311 amino acids)

>Dsui_0987 Zn-dependent hydrolase, glyoxylase (Dechlorosoma suillum PS)
MASSRSVAPPPRLPASLLVLERGWLSSNNVLCIEDEEAALVDSGYVTHAAQTLALVEKAL
DGRRLTRLINTHSHSDHIGGNAALKHATGCRVLVPAGMAATIAEWDEEALLLSPLGQQAA
RFQHDATLAAGDRLTLGGLEWQALAVPGHDMDALAYFNADQGILISGDALWQDGFGVIFA
ELLGGDGLRTTRQTLDMLAALPIRAVIPGHGAPFADIGESFERAYSRLAGFESSIERLAR
HALKVMLVFYLLEKRRVQRRELPGLIASLSFPRSVAARYLAMDEEETAEWLTADLLRAGV
LQEEEGWLVAR