Protein Info for Dsui_0819 in Dechlorosoma suillum PS

Annotation: DNA protecting protein DprA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 372 TIGR00732: DNA protecting protein DprA" amino acids 70 to 285 (216 residues), 254 bits, see alignment E=4.5e-80 PF02481: DNA_processg_A" amino acids 75 to 277 (203 residues), 254 bits, see alignment E=8.4e-80 PF17782: DprA_WH" amino acids 306 to 364 (59 residues), 65 bits, see alignment E=5.2e-22

Best Hits

KEGG orthology group: K04096, DNA processing protein (inferred from 59% identity to eba:ebA2961)

Predicted SEED Role

"Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QHS5 at UniProt or InterPro

Protein Sequence (372 amino acids)

>Dsui_0819 DNA protecting protein DprA (Dechlorosoma suillum PS)
MADPALTAWLRLTLVPGVGPETQRHLLAAFGLPEQVFSAPRSALKQVVGKKADLLLDTDN
QEAVDRALDWAGKPGNRILTLADPDYPQLLLESADPPSLLYVKGRVELLNRPALAIVGSR
NATPQGLKDAEALAADLAAQGLTIVSGLALGIDGAAHRGGLKGEGGSVAIIGTGADRIYP
SRHKELALQLATEGAIVSEFPLGTPAVAHNFPRRNRIIAGMAKGCLVVEAALESGSLITA
RLAAELGREVFAIPGSIHSPVAKGCHRLIQQGAKLVQEARDIVEEIGPFDPPGCKPARTP
LSTGNTPTTAPILDPGQAAVLDALGHDPANLDQLLQRTGLTTEALCAILVTLELADRVAS
LPGGRYQRLSPT