Protein Info for Dsui_0501 in Dechlorosoma suillum PS

Annotation: glycine/D-amino acid oxidase, deaminating

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00070: Pyr_redox" amino acids 2 to 33 (32 residues), 23.9 bits, see alignment (E = 2e-08) PF01266: DAO" amino acids 2 to 398 (397 residues), 240 bits, see alignment E=2.3e-74 PF02558: ApbA" amino acids 3 to 64 (62 residues), 26.6 bits, see alignment E=1.6e-09 PF00890: FAD_binding_2" amino acids 3 to 46 (44 residues), 23 bits, see alignment 1.8e-08 PF13450: NAD_binding_8" amino acids 5 to 35 (31 residues), 25.7 bits, see alignment (E = 4.4e-09) PF01593: Amino_oxidase" amino acids 200 to 256 (57 residues), 23.5 bits, see alignment 1.3e-08

Best Hits

Swiss-Prot: 66% identical to DADA_DECAR: D-amino acid dehydrogenase (dadA) from Dechloromonas aromatica (strain RCB)

KEGG orthology group: K00285, D-amino-acid dehydrogenase [EC: 1.4.99.1] (inferred from 66% identity to dar:Daro_3842)

Predicted SEED Role

"D-amino acid dehydrogenase small subunit (EC 1.4.99.1)" in subsystem Pyruvate Alanine Serine Interconversions or Respiratory dehydrogenases 1 (EC 1.4.99.1)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QFA5 at UniProt or InterPro

Protein Sequence (416 amino acids)

>Dsui_0501 glycine/D-amino acid oxidase, deaminating (Dechlorosoma suillum PS)
MRVLVLGAGVVGVTSAWFLAEAGHEVTVVDRQPGAALETSFANGGQISVCHAEPWANPRA
PFKALEWLGKEDAPLLFRLRYDPALFAWSLRFLANCPPGATRRNIRDIIALALYSRQRLQ
ALRQALPLDYDQRCQGILHIFTQAAEFEAACHAAALMREFGVDREPVDAARCVAIEPALA
AVQGRLAGGDYTPSDESGDAHRFTQRLAEAAAARGVQFRYNCPVEKIASAGGRVAGVVAG
GDLLLADAYVVALGSYSPALLKPAGVKACVYPGKGYSATIALSPDSVAPSVSITDDERKI
VMSRLGNRLRVAGTAEFNGHNLDLTPVRCEALLRRALELFPQLRPDGDPLYWCGLRPVTP
SNVPLIGRTRLSNLWLNTGHGTLGWTLSCGSAAALADLISGRRPEPDFPFLGTTKQ