Protein Info for Dsui_0480 in Dechlorosoma suillum PS

Annotation: periplasmic protein TonB, links inner and outer membranes

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 266 transmembrane" amino acids 14 to 34 (21 residues), see Phobius details PF13103: TonB_2" amino acids 173 to 255 (83 residues), 64.6 bits, see alignment E=3.8e-22

Best Hits

KEGG orthology group: None (inferred from 50% identity to dar:Daro_4054)

Predicted SEED Role

"TolA protein" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QPN8 at UniProt or InterPro

Protein Sequence (266 amino acids)

>Dsui_0480 periplasmic protein TonB, links inner and outer membranes (Dechlorosoma suillum PS)
MPFERRAEPGKRKALILAILVHLLLAIFLFFGIRWQTKHEAVEVELWSDVPQGAYKPPPP
PPEPKPVPKPEPKPEPKPEVKPDPKPASKPDIVLKEEKKKPEPKKEEPKPEPKKEEKKLE
TPDWQKELERDQRDLKQRQREQALKEQLSREMNMQQAAGKEAAAASSRSKGLASYVDKIR
AKVRGNLGFVSVSGNPTAKFLVTQLPSGEIISARMTRSSGVPAYDSAVERAIMKSSPLPL
PDDKSAFHRELELTFCPQEGTSGCSP