Protein Info for Dsui_0408 in Dechlorosoma suillum PS

Annotation: cation/multidrug efflux pump

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1067 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details transmembrane" amino acids 337 to 356 (20 residues), see Phobius details amino acids 363 to 383 (21 residues), see Phobius details amino acids 389 to 413 (25 residues), see Phobius details amino acids 434 to 453 (20 residues), see Phobius details amino acids 465 to 489 (25 residues), see Phobius details amino acids 556 to 576 (21 residues), see Phobius details amino acids 887 to 907 (21 residues), see Phobius details amino acids 915 to 935 (21 residues), see Phobius details amino acids 941 to 962 (22 residues), see Phobius details amino acids 987 to 1009 (23 residues), see Phobius details amino acids 1015 to 1037 (23 residues), see Phobius details PF00873: ACR_tran" amino acids 7 to 1038 (1032 residues), 544.3 bits, see alignment E=5.2e-167 PF03176: MMPL" amino acids 858 to 1041 (184 residues), 23 bits, see alignment E=3.6e-09

Best Hits

KEGG orthology group: None (inferred from 57% identity to abc:ACICU_03646)

Predicted SEED Role

"RND efflux transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QP23 at UniProt or InterPro

Protein Sequence (1067 amino acids)

>Dsui_0408 cation/multidrug efflux pump (Dechlorosoma suillum PS)
MKRFNISEWGLRHPALVLYFMVALTLVGLLAYSKLGQSEDPPFTFKVMVVRTAWPGASAQ
EVERQVTEKIEKTLQSVPYADIIRSYSRPGESMIFFQAKDATPAAAVPDIWYQVRKKVGD
MRYTLPKGIEGPTFNDEFGDVYGNLYAVVGDGFGYTELKRQAEAIRAELLRVKDVAKVDF
FGEQKERVYIELSNAKLATLGIDGAAVVAALQNQNAVLAAGSFDTPSEHIRIDVSGRYDD
LTALRETRLRANGREVRLGDIASIGRGYEDPPTQKIRYMGKEAVLIGVSMAKGGDIIRLG
GGLDGAVASIQDRLPVGLELHTVSSQPQAVQRSVNEFVRSLIEAVIIVLGVSLLSLGLRT
GIVVAITIPVVLAITFLFMQIFGVGLHKISLGALILALGLLVDDAIIAVEMMATKMEQGW
ARAKAASFAYESTAMPMLSGTLVTAAGFLPIATAASATGEYTRSIFQVTVIALLISWVAA
VLFVPYLGYKLLPDFAHHRVAHQEPGRLSRWLMRRLPWLERWLHKEPHTHSEHDIYATPF
YRRFRALVDACVRRRWLVIGITVGAFVASIVGFGLVQQQFFPDSTRPELIVDLRLAEGAS
WDAADAEAKRLESWLAEQPGIDNVVAYVGTGSPRFYLPLDQQMPQKNFAQFVILTQGSPE
RETLRSKLIDLFEHDFPSLRAAINRLENGPPVGFPVQFRVAGPDLNVLRGYAHEVAQVMR
ANPSLANVHLDWEEPAKVVRLTVDQSKARLLGVTSSDIANLINTALKGQSVTEFRDGAEL
VDVHLRGTEMERRRLSLLPDLMLPTRAGKAVPLSQVATLEYGFEEGIVWRRNRVPTITVR
GNIYGHMQGPVVSAQVEKSLQSIKASLPLGYTLEVGGAVEESAKGGASVAAGVPLFFLVV
LTVLMLQLQSFSKVAMVLLTAPLGLVGVTAFLLLFNKPFGFVAMLGTIALSGMIMRNSVI
LVDQIDQDEKAGKPRWEAIVDSTVRRLRPIVLTAAAAILAMIPLTRSAFFGPMAVAIMGG
LTVATLLTLIFLPALYAAWHKVKPAAPAESLQTVDETLAGSRQGPQL