Protein Info for Dsui_0400 in Dechlorosoma suillum PS

Annotation: putative nucleoside-diphosphate sugar epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 620 transmembrane" amino acids 22 to 42 (21 residues), see Phobius details amino acids 55 to 77 (23 residues), see Phobius details amino acids 92 to 112 (21 residues), see Phobius details amino acids 119 to 138 (20 residues), see Phobius details amino acids 150 to 161 (12 residues), see Phobius details PF13727: CoA_binding_3" amino acids 74 to 226 (153 residues), 44.3 bits, see alignment E=7.4e-15 PF08659: KR" amino acids 294 to 419 (126 residues), 31.8 bits, see alignment E=4.7e-11 PF04321: RmlD_sub_bind" amino acids 294 to 483 (190 residues), 56.2 bits, see alignment E=1.1e-18 PF01370: Epimerase" amino acids 295 to 508 (214 residues), 83 bits, see alignment E=8e-27 PF02719: Polysacc_synt_2" amino acids 295 to 578 (284 residues), 399.3 bits, see alignment E=3.4e-123 PF16363: GDP_Man_Dehyd" amino acids 296 to 420 (125 residues), 45.9 bits, see alignment E=1.9e-15 PF01073: 3Beta_HSD" amino acids 296 to 426 (131 residues), 35.5 bits, see alignment E=2.1e-12

Best Hits

KEGG orthology group: None (inferred from 62% identity to slt:Slit_2880)

Predicted SEED Role

"UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-)" in subsystem N-linked Glycosylation in Bacteria (EC 4.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.2.1.-

Use Curated BLAST to search for 4.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QP15 at UniProt or InterPro

Protein Sequence (620 amino acids)

>Dsui_0400 putative nucleoside-diphosphate sugar epimerase (Dechlorosoma suillum PS)
MPDSHQGDSAQKAFLGLISRRFIASAYDLVALIVCWLAAYWLRFNLSLPDEYLRAGLFSL
AILVPVYVPLFWLSGLYRGIWRYASLMDLRRIIVSVGLGGLVTAVAVFMTGMPGVPRSVL
VLHPILLILAMGGGRFLYRAWKDRCLYGHLALSGESVLILGAGEVGERLIRELQRSPQWR
VAGLLDNDPAKHGREVHGVKIRGDIASMVHWAKELEVGHVIVAMPSVSAAVRRGAMEQAV
QAGLKVLTVPALDDLLSGRVSLSQIRQVELEDILGREPVQLDDAGLSRLIAERTILVTGA
GGSIGSELARQIARFAPRQLVLFEVSEFALYQIEQEFRRTFPGLDVVCVVGDVKDEARLQ
QVFAAYRPALVFHAAAYKHVPLMESANAWEAVRNNVLGTWRVAMAARQAGVEKMVLISTD
KAVNPTNVMGTTKRMAERVVQSLEQAGGGTQFIVVRFGNVLGSNGSVIPTFREQIARGGP
VTVTHPDIIRYFMLIPEAAQLVLQAGLMGNGGEIFVLDMGEPVKIVDLARDLIRLSGFTE
EEIPIEFTGLRPGEKLYEELLADNEMTLPTPHAKLRVAKAESAPEEAWIGDLARWLETPP
ADVAGIKAGLARFVPEYRPQ