Protein Info for Dsui_0278 in Dechlorosoma suillum PS

Annotation: K+-transporting ATPase, B subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 692 transmembrane" amino acids 34 to 54 (21 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 219 to 244 (26 residues), see Phobius details amino acids 258 to 283 (26 residues), see Phobius details amino acids 597 to 618 (22 residues), see Phobius details amino acids 624 to 645 (22 residues), see Phobius details amino acids 665 to 689 (25 residues), see Phobius details TIGR01497: K+-transporting ATPase, B subunit" amino acids 7 to 686 (680 residues), 1080.7 bits, see alignment E=0 TIGR01494: HAD ATPase, P-type, family IC" amino acids 72 to 349 (278 residues), 106.7 bits, see alignment E=1e-34 amino acids 380 to 611 (232 residues), 144.5 bits, see alignment E=3.7e-46 PF00122: E1-E2_ATPase" amino acids 117 to 291 (175 residues), 104 bits, see alignment E=7e-34 PF00702: Hydrolase" amino acids 307 to 540 (234 residues), 91 bits, see alignment E=1.3e-29

Best Hits

Swiss-Prot: 76% identical to KDPB_DECAR: Potassium-transporting ATPase ATP-binding subunit (kdpB) from Dechloromonas aromatica (strain RCB)

KEGG orthology group: K01547, K+-transporting ATPase ATPase B chain [EC: 3.6.3.12] (inferred from 77% identity to mca:MCA2216)

MetaCyc: 73% identical to K+ transporting P-type ATPase subunit KdpB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-2 [EC: 7.2.2.6]

Predicted SEED Role

"Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12 or 7.2.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QNA3 at UniProt or InterPro

Protein Sequence (692 amino acids)

>Dsui_0278 K+-transporting ATPase, B subunit (Dechlorosoma suillum PS)
MKTTSQSLYDRALLQEAAWESVKRLSPRYQVKNPVMFVVWLGSLLTTGLWLQALAGEGEA
PAGFILAITLWLWFTVLFANFAEAVAEGRGKAQAAALKGLKKTVWAKKLREAHAGAPFHT
VPSEDLRKGDVVLVQAGDVIPGDGEVVEGVASVDESAITGESAPVIRESGGDFSAVTGGT
RVLSDWLVVKITVNPGETFLDRMIGMVEGARRQKTPNEIALTILLVALTLTFLLATATLL
PFSIYSVGVAGSGSPVTVTVLVALLVCLIPTTIGGLLSAIGVAGMGRMMEKNVIATSGKA
VEAAGDVDVLLLDKTGTITLGNRQAAAFAPAAGVSEKELAEAALLASLADETPEGRSIVT
LAKERLHQRGRDIHADGASFVHFTAQTRMSGIDWQGRCIRKGAADAVKAHIQALGGEWSA
AVQQAVDDIARRGATPLAVAESSAGAARVLGVVELKDIVKGGIKERFAELRRMGIKTVMI
TGDNSLTAAAIAAEAGVDDFLAEATPEAKLKLIRQHQQDGRLVAMTGDGTNDAPALAQAD
VAVAMNSGTQAAKEAGNMVDLDSNPTKLIEIVETGKQMLMTRGALTTFSIANDVAKYFAI
IPAAFAATYPALGVLNVMGLATPASAILSAVIFNALVIVALIPLALKGVAYRPQGAAAIL
RRNLLVYGLGGLVVPFAGIKAIDLMLVGLHLA