Protein Info for Dsui_0173 in Dechlorosoma suillum PS

Annotation: site-specific DNA methylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 602 PF00145: DNA_methylase" amino acids 18 to 220 (203 residues), 38.7 bits, see alignment E=4.3e-14

Best Hits

KEGG orthology group: None (inferred from 72% identity to reu:Reut_A2369)

Predicted SEED Role

"C-5 cytosine-specific DNA methylase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QM77 at UniProt or InterPro

Protein Sequence (602 amino acids)

>Dsui_0173 site-specific DNA methylase (Dechlorosoma suillum PS)
MKRDAFTLAPDDVREIRHFHLFCGLGGGAKGFNKASPRVGNMVGKFRCIGGVDVDPAAIR
DFQRLTGTPGTVLDLFDRSQYQAFHGMEPPAGWREVGPAEIRAAAGGEYPHIVFLSAPCK
GFSGLLSENRSRTDKYQALNRLTLRGIWLMLEAFADEPPELIVFENVPRIANRGRHLLDQ
IGDLLQSYGYAVAETTHDCGELGALAQSRKRFLLVARHVAKVQPFLYEPEKKSLAAVGTV
LDRMPLPGDPAGGPMHRIPRLQWQTWVRLAFVEAGSDWRSLNRLAVEDGVLRDFLIVPEH
FHNGYMGVNRWEDPMGTVRGRSLPLNGAFSVADPRYQGHEYQQYGVRRWEDTCGAVSSQS
APGGGAYSVADPRHTGPAKHSNEFRIVPWSEEARAVTGAHGSGQCVADPRRAGEGFGKYM
VTGYRQPAGTVISGSTTGQGAYAVADPRPSLERGKGDHYLTGGHYGVAKWEEPSGAVSAA
ACHDNGRWSVADPRMPAAADNLVAVIRALDGTWHRPFTTLELAALQSLVDPEEHLELDGL
SDSDWRERIGNAVPPDAAQAIAGVMGTTLLLAWSGETFMLSSAPIWVRPVAVALSVAQGG
AA