Protein Info for Dsui_0028 in Dechlorosoma suillum PS

Annotation: putative effector of murein hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 transmembrane" amino acids 16 to 42 (27 residues), see Phobius details amino acids 54 to 73 (20 residues), see Phobius details amino acids 80 to 99 (20 residues), see Phobius details amino acids 108 to 130 (23 residues), see Phobius details amino acids 132 to 133 (2 residues), see Phobius details amino acids 164 to 186 (23 residues), see Phobius details amino acids 198 to 215 (18 residues), see Phobius details amino acids 221 to 246 (26 residues), see Phobius details PF04172: LrgB" amino acids 31 to 244 (214 residues), 264.9 bits, see alignment E=2.3e-83

Best Hits

Swiss-Prot: 41% identical to YOHK_SHIFL: Inner membrane protein YohK (yohK) from Shigella flexneri

KEGG orthology group: None (inferred from 76% identity to azo:azo1154)

Predicted SEED Role

"LrgA-associated membrane protein LrgB" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QKR5 at UniProt or InterPro

Protein Sequence (251 amino acids)

>Dsui_0028 putative effector of murein hydrolase (Dechlorosoma suillum PS)
MSAPLATALGAPLAQIWVYLSASPLLGLTVTLLAYQGAFALYRKAKFHPAANPVLLAVAF
LVALLAITGTPYQTYFDGAQFVHFLLGPATVALAIPLYAQIKRVKAMFWPILIALVAGCL
TAALSAMAVGKLFGASLATLLSLAPKSVTTPIAMGIAERTGGLPSLTAVLVITTGILGAV
GARYLFDALNIKDHAVRGFAIGIASHGIGTARAFQVSEQCGAFAALAMGLNGALTALLLP
VVLPWVKSWLG