Protein Info for CSW01_19385 in Vibrio cholerae E7946 ATCC 55056

Annotation: tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 PF04013: Methyltrn_RNA_2" amino acids 5 to 203 (199 residues), 286.5 bits, see alignment E=5.7e-90

Best Hits

Swiss-Prot: 100% identical to TRMYL_VIBCH: Putative pseudouridine methyltransferase (VC_A1059) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_A1017)

Predicted SEED Role

"protein of unknown function DUF358"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (205 amino acids)

>CSW01_19385 tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY (Vibrio cholerae E7946 ATCC 55056)
MRNTMRSFILRARSAPTDSQRLLDEIGGKCHTEILAHCMMNSLFTAQSHREDVVIHLVLE
STRDYSRTITVEANEISDVGGFHEAALIALLVKALDASVGMGKEQTRVVQPGLTVRTISF
EALLGELAEHHSLYMMDKKGDSIRDIKIGPNPCFILTDHIPMPKKSGNSMKRLGVEKISL
GPKMLFASQCVTLIHNEIDHQEAGW