Protein Info for CSW01_18850 in Vibrio cholerae E7946 ATCC 55056

Annotation: maltose ABC transporter permease MalF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 524 transmembrane" amino acids 24 to 44 (21 residues), see Phobius details amino acids 50 to 68 (19 residues), see Phobius details amino acids 78 to 101 (24 residues), see Phobius details amino acids 290 to 314 (25 residues), see Phobius details amino acids 325 to 349 (25 residues), see Phobius details amino acids 378 to 402 (25 residues), see Phobius details amino acids 436 to 457 (22 residues), see Phobius details amino acids 495 to 516 (22 residues), see Phobius details PF20872: MalF_N_TM" amino acids 24 to 71 (48 residues), 77.7 bits, see alignment 6.7e-26 PF14785: MalF_P2" amino acids 110 to 270 (161 residues), 210.5 bits, see alignment E=2.3e-66 PF00528: BPD_transp_1" amino acids 307 to 512 (206 residues), 59.3 bits, see alignment E=6.5e-20

Best Hits

Swiss-Prot: 100% identical to MALF_VIBCH: Maltose/maltodextrin transport system permease protein MalF (malF) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K10109, maltose/maltodextrin transport system permease protein (inferred from 100% identity to vch:VCA0944)

Predicted SEED Role

"Maltose/maltodextrin ABC transporter, permease protein MalF" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (524 amino acids)

>CSW01_18850 maltose ABC transporter permease MalF (Vibrio cholerae E7946 ATCC 55056)
MQSVQGTQAMSDPTAVRPADKRAFLKWAVLGAVGIVNGYATILMYSRGEVAFALLTLILT
TLALYIFGSRKTYAHRYIYPGIAGMILFILFPLAYTVGLAFTNYSAKNQLTLERAQSVLM
DQTFQSGESYAFQLYKTEQGYRLLIEDGDERLATAPFSLSGNVPTDLNLEVIGGIDGEVE
PIKTIIGYRTELSGIDLHFPDGEDIRMSGLRKFAAVKPLYTLQDDGETLTNNQSGQVLRP
NMEIGFYQPINESGEFVGERVSPGFVVSIGTHNFERVWKDEGIKEPFINIFIWTVIFSVL
TVIFTLMIGLVLASVVQWEALKGRAVYRVLLILPYAVPAFISILIFRGLFNQSFGEINMV
LNGLFGLSPAWFSDPLLAKTMVLIVNTWLGFPYMMILCMGLLKAIPDDLYEASAIDGANF
IHNFTKITLPMMIKPLTPLLIASFAFNFNNFVMIQLLTQGGPNRIGTSEPAGYTDLLVSY
TYRIAFEGTGGQDFGLASAIATLIFLLVGALALLNLRFTKLSQQ