Protein Info for CSW01_18465 in Vibrio cholerae E7946 ATCC 55056

Annotation: outer membrane protein W

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 217 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF13505: OMP_b-brl" amino acids 8 to 198 (191 residues), 58.9 bits, see alignment E=7.5e-20 PF03922: OmpW" amino acids 23 to 217 (195 residues), 270.6 bits, see alignment E=8.7e-85

Best Hits

Swiss-Prot: 100% identical to OMPW_VIBCH: Outer membrane protein W (ompW) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K07275, outer membrane protein (inferred from 100% identity to vcj:VCD_000465)

Predicted SEED Role

"Outer membrane protein W precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (217 amino acids)

>CSW01_18465 outer membrane protein W (Vibrio cholerae E7946 ATCC 55056)
MKQTICGLAVLAALSSAPVFAHQEGDFIVRAGIASVVPNDSSDKVLNTQSELAVNSNTQL
GLTLGYMFTDNISFEVLAATPFSHKISTSGGELGSLGDIGETKHLPPTFMVQYYFGEANS
TFRPYVGAGLNYTTFFDESFNGTGTNAGLSDLKLDDSWGLAANVGFDYMLNDSWFLNASV
WYANIETTATYKAGADAKSTDVEINPWVFMIAGGYKF