Protein Info for CSW01_18220 in Vibrio cholerae E7946 ATCC 55056

Annotation: peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00089: Trypsin" amino acids 165 to 357 (193 residues), 22.2 bits, see alignment E=1.6e-08 PF13365: Trypsin_2" amino acids 175 to 334 (160 residues), 47.6 bits, see alignment E=4.5e-16 PF04151: PPC" amino acids 402 to 458 (57 residues), 37.5 bits, see alignment 5.6e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to vco:VC0395_0422)

Predicted SEED Role

"Cold-active serine alkaline protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (476 amino acids)

>CSW01_18220 peptidase (Vibrio cholerae E7946 ATCC 55056)
MMKSKIVTATLALCCLSPSFSYAQSTAPTIADEVIFTLSSETLTSPRAVVEHPKADFIKL
HFKSLNLPQGSAIRLTSRDGTEVVQYTESQQSWFAQSLFGDQVLIELIPNAKGEIGQFEI
DYYMAGNESLAESELLSTCGINERKDVACWQDSHPEKVSWSSPVARLLINGRSLCTAWRV
GPDNRLFTNNHCVSTASELKQTEVWFNYQRTTCNGSLATTVKVMGNELLSTDYTLDYTLF
TVDDFNKIASFGYLGLDNTEPVFGNGIYIPQHGAGNPKELAIESDKNGSGLCQIDIASTN
GRGTHTDTGYFCDTIGGSSGSPVLNTSDNKAIALHHFGGCENQGVKISKIWTKVATFFNH
TLPNGSVSQTPPQVRELIPNQPLNNLALSQGEEMLLMVKASNRKTNLTISISSGSGDADL
YVKTGQPPTQSLYDCRPYQSTNNETCVAPLVNEDLYIMLRAYRSFAGVSLTATEKQ