Protein Info for CSW01_17930 in Vibrio cholerae E7946 ATCC 55056

Annotation: thioredoxin TrxC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 144 PF21352: Thio2_N" amino acids 8 to 32 (25 residues), 44.2 bits, see alignment 2.8e-15 PF00085: Thioredoxin" amino acids 43 to 139 (97 residues), 95.8 bits, see alignment E=2.9e-31 TIGR01068: thioredoxin" amino acids 45 to 141 (97 residues), 117 bits, see alignment E=1.9e-38 PF13098: Thioredoxin_2" amino acids 53 to 138 (86 residues), 42.2 bits, see alignment E=1.8e-14

Best Hits

Swiss-Prot: 56% identical to THIO2_ECO57: Thioredoxin 2 (trxC) from Escherichia coli O157:H7

KEGG orthology group: K03672, thioredoxin 2 [EC: 1.8.1.8] (inferred from 100% identity to vco:VC0395_0690)

MetaCyc: 56% identical to reduced thioredoxin 2 (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Thioredoxin 2 (EC 1.8.1.8)" (EC 1.8.1.8)

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.8

Use Curated BLAST to search for 1.8.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (144 amino acids)

>CSW01_17930 thioredoxin TrxC (Vibrio cholerae E7946 ATCC 55056)
MSTFNTRCPSCHSLNRVPEERITESPNCGKCQSALLDGAPIEGTEANFSALLQSDKPVVV
DFWAPWCNPCVGFAPIFSDVAAERKGQIRCVKIDTEAQQNLAAHFQIRSIPTIMVFKNGQ
RIDMINGALPKSQFDQWLNQALTK