Protein Info for CSW01_17130 in Vibrio cholerae E7946 ATCC 55056

Annotation: Zn-dependent protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01435: Peptidase_M48" amino acids 59 to 247 (189 residues), 157.2 bits, see alignment E=2.2e-50

Best Hits

KEGG orthology group: None (inferred from 99% identity to vco:VC0395_0525)

Predicted SEED Role

"Zn-dependent protease with chaperone function PA4632"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (263 amino acids)

>CSW01_17130 Zn-dependent protease (Vibrio cholerae E7946 ATCC 55056)
MKKTQLALTLLMTLGLAACSASPTGRNQLLLFSDNDMSQLGAKSFTQMKQEIPISKDAKT
NAYVQCVTKAIIAQVPKQSSFEQWEVVVFESDQVNAFALPGGKIGVYTGLLKVAVNQDQL
ATVIGHEIAHVLSNHSNERLSQSQLANAGLQLTDIAIGASEYAQYRNLTMSALGVGVQYG
VILPYGRSQESEADILGLALMARAGFDPYQSIELWKNMAKASGGKQPPELLSTHPSHSTR
ISDLSATISTLPPHQGSKAQCAL