Protein Info for CSW01_16975 in Vibrio cholerae E7946 ATCC 55056

Annotation: site-2 protease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 transmembrane" amino acids 130 to 159 (30 residues), see Phobius details amino acids 170 to 188 (19 residues), see Phobius details amino acids 200 to 222 (23 residues), see Phobius details amino acids 228 to 248 (21 residues), see Phobius details amino acids 266 to 284 (19 residues), see Phobius details amino acids 288 to 306 (19 residues), see Phobius details amino acids 327 to 346 (20 residues), see Phobius details PF02163: Peptidase_M50" amino acids 148 to 221 (74 residues), 50.1 bits, see alignment E=1.2e-17 amino acids 227 to 266 (40 residues), 35 bits, see alignment 5e-13

Best Hits

KEGG orthology group: None (inferred from 99% identity to vco:VC0395_0483)

Predicted SEED Role

"Zn-dependent protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (360 amino acids)

>CSW01_16975 site-2 protease family protein (Vibrio cholerae E7946 ATCC 55056)
MELLCIDYLGKPLRLEGTMAGWQQLFWDNILVAQRPAQEQYEGDIQHHFQLTQGEHVLEC
CLEIALTWQPFQLQYQTKLNGELVAQGMRSEKDVERQTPYEAPKVERRFSVIGLVSLAMK
ALKSAKMIKVVMASASLAAYSWLFSFQFALALIGCLVFHEYGHVRAMKYFGMKTKGIYLV
PFLGGLALSDEKINTRWQDVVISIMGPCFGFLLSLLLVGVYWVTDSPFWAALAVFNAFLN
LFNLLPVLPLDGGHILKSVSFSMNSKMGVILCVLAILGGIALSYSLGLTLFGFLLLMGAL
DIVFEWRQRHHSHLLPLNRYAQMVSTIWYFALVSGLIAIIIGFASTGDTLLSLPLLILGT