Protein Info for CSW01_16960 in Vibrio cholerae E7946 ATCC 55056

Annotation: DUF475 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details amino acids 34 to 56 (23 residues), see Phobius details amino acids 75 to 97 (23 residues), see Phobius details amino acids 109 to 129 (21 residues), see Phobius details amino acids 135 to 154 (20 residues), see Phobius details amino acids 197 to 221 (25 residues), see Phobius details amino acids 228 to 248 (21 residues), see Phobius details amino acids 255 to 275 (21 residues), see Phobius details amino acids 281 to 304 (24 residues), see Phobius details TIGR03718: integral membrane protein, TerC family" amino acids 3 to 307 (305 residues), 344.4 bits, see alignment E=3.3e-107 PF03741: TerC" amino acids 76 to 275 (200 residues), 183.6 bits, see alignment E=1.6e-58

Best Hits

KEGG orthology group: K05794, tellurite resistance protein TerC (inferred from 100% identity to vcm:VCM66_A0505)

Predicted SEED Role

"Integral membrane protein TerC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (318 amino acids)

>CSW01_16960 DUF475 domain-containing protein (Vibrio cholerae E7946 ATCC 55056)
MSPITYLGFGLLTLTLVAVDLWQTRGGNVTIKKAAIWSIAWFLLAFVFAISLYYGWQWYA
PHSSYSAEKATLSFITGYLLEKSLSVDNLFVFAIIFHQYSVPEHLRPRALLWGVIGALVL
RAIMIAVGAQLLSQYHWILYVFALFLIWTGIQLARDKGEESINPLPERWIRRCFNVTKEY
QGNALICKQQGQWWVTPMFIVIGVIAFMDVMFALDSIPAIFAMTQEPFLVLAANVFALLG
LRSLYFVLQGMMDKFFYLKPALAFIMMFIGVKMMLVDSAWAIPTPISLCVLLVTMSTAVI
ASVLRERSQSKPIAEKVS