Protein Info for CSW01_16795 in Vibrio cholerae E7946 ATCC 55056

Annotation: nucleotide pyrophosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 968 transmembrane" amino acids 21 to 38 (18 residues), see Phobius details amino acids 73 to 91 (19 residues), see Phobius details PF01663: Phosphodiest" amino acids 390 to 654 (265 residues), 40.8 bits, see alignment E=1.1e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to vch:VCA0510)

Predicted SEED Role

"FIG01199913: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (968 amino acids)

>CSW01_16795 nucleotide pyrophosphatase (Vibrio cholerae E7946 ATCC 55056)
MTHYQTEIGKIMYSSHQCKRLSIMAILGCLPFSVNGAVESMPLMGGVYNSAHVFKHQITN
SLSYSTRLTRDTALFTIAGLTLDSYILTLPLDVKTKARVIKQISDPSYAIPLGYFLYQYY
DRYTGMATEDQFKNYLSTVYDEPALKGFEHSLFQLGKPVVTEQSQHSKDQAHQEGIKVDS
EFIATMVTLYDALVQIGEWRDLKQLPSQYQYLSDTPADNALVSKIQPLVVDILRQTANGM
DEGEMKHALLSVLEDAKPENANKVNNKAQAITVSLIDFVRLNVLKGYRQFLYQEERTARL
KEWLNKTLDSDPEQLVTFLTSQQQRRFAVQVTVDGLQQGLIEGLVHPENPFIKQVYAEHQ
QAEKNQHSTLMEPLEHKQQVRFLSTLAEQNYQDPYYLPFFKQLYQHYRQTIVQVGISSTP
TISVRNLPIIKTGAKVSGLGGTGIPNFHFVDRQADRAYYFFGNDALQLDRLVNERGVKTM
FDRLDYLKTLNCNAQYDWNAHTTYDGLVNLGAGEALRDFGEKRCLRELNERAEEERQLTA
LRAKLIEQITAYQNSSKWMVLTRATLKQRLEQQLAEYAERDIFGMPDYTLIYNPWPDHFA
HFAGPFSDEVIMPTGELNRLDYWLRETEAAYKKAGIYERTLWGMAGDHGLAPVYGTLNPE
RKIFESLQKDLGIKIALEKISSDEGEGPKLTNALNAPSYQKIDVVVASTAGGNFMLDFFN
SAAGWATQPIYQELTQWQPKESDKPLDIVSESLVRLGDSLDYLVVREKTCTVDDCAVRVI
GMREGLRLDEIIRLVGNKRFYTSQQGQPQLLQLQQLNPYLPKPQANALEEFAQLVDKCLY
RAEEANIATWCDEQEWRQLTRFTPRPDSVNQLAALYEEDRAGTMNLFPKQGVGYNTKVPG
RHAGESYLEKDAFLGFWGKPIGPNAMALQSEQNGSLAPTLYEYLTGESIEAGHDGWGYPS
LLNKLDIQ